Testolactone manufacturers and suppliers in india

Testolactone

CAS:: 968-93-4

MF:: C19H24O3

MW:: 300.39

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Properties

Melting point:: 218-219°

alpha: D23 -45.6° (c = 1.24 in chloroform)

Boiling point:: 482.0±45.0 °C(Predicted)

Density: 1.17±0.1 g/cm3(Predicted)

solubility: Chloroform (Sparingly), Methanol (Slightly)

form: Solid

color: White to Off-White

Safety Information

HS Code: 2937290000

Use

Testolactone, 13-hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acidΔ-lactone (Teslac),was originally synthesized as a possible anabolic steroid,considering its structural similarity to testosterone. The keystructural difference from anabolic steroids is the D-ring lactone instead of the typical cyclopentyl ring. Althoughconsidered in many texts an androgen or anabolic steroid (itis a Schedule III drug because of its classification as an anabolicsteroid), testolactone lacks androgenic effects in vivo.Its action is believed to be caused by irreversible inhibitionof aromatase. It is a relatively weak inhibitor of aromatase,but the irreversible nature of the inhibition can lead to prolongedeffects. Its relatively weak inhibition of aromataseand its undesirable dosage schedule (5×50-mg tabletsq.i.d.) give this older agent only limited use in breast cancertreatment because of better available options.