Thiamphenicol
Thiamphenicol
- CAS:
- 15318-45-3
- MF:
- C12H15Cl2NO5S
- MW:
- 356.22
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Company Type
Properties
- Melting point:
- 163-166 °C
- alpha
- D25 +12.9° (ethanol)
- Density
- 1.3281 (rough estimate)
- refractive index
- 1.6000 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- ethanol: 50 mg/mL, clear, colorless
- Boiling point:
- 695.9±55.0 °C(Predicted)
- pka
- 11.05±0.46(Predicted)
- form
- powder
- color
- white to off-white
- Water Solubility
- Soluble in acetonitrile or DMF. Slightly soluble in water
- Merck
- 14,9301
- BRN
- 2819542
- InChIKey
- OTVAEFIXJLOWRX-NXEZZACHSA-N
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
- Safety Statements
- 22-24/25
- WGK Germany
- 2
- RTECS
- AB6680000
- HS Code
- 29414000
- Toxicity
- human,TDLo,unreported,214mg/kg/10D (214mg/kg),BEHAVIORAL: SLEEPGASTROINTESTINAL: NAUSEA OR VOMITINGSKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE",Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 944, 1974.
Use
Thiamphenicol is a semi-synthetic chloramphenicol prepared by total synthesis from thiophenol in which the nitro moiety of chloramphenicol is replaced by a methylsulphone, first synthesised at Sterling Winthrop in 1952. Thiamphenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Thiamphenicol acts by binding to the 23S sub-unit of the 50S ribosome inhibiting protein synthesis. Thiamphenicol has been extensively studied with over 800 literature citations.
3 India supplier list of "Thiamphenicol"
- Product Name:Thiamphenicol
- Products Intro:Brand:sigma aldrich | Product Number:16715 | Purity:analyticalstandard
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Thiamphenicol
- Products Intro:Brand:synzeal | Product Number:192381950
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Thiamphenicol
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Thiamphenicol
- Products Intro:Brand:pharmaffiliates | Product Number:PA0339630
- Company Type: Trader
- Country/Region: INDIA