Thioridazine hydrochloride
Thioridazine hydrochloride
- CAS:
- 130-61-0
- MF:
- C21H27ClN2S2
- MW:
- 407.04
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Company Type
Properties
- Melting point:
- 158-1600C
- Boiling point:
- 230°C (rough estimate)
- Density
- 1.1227 (rough estimate)
- refractive index
- 1.5610 (estimate)
- storage temp.
- 2-8°C
- solubility
- H2O: soluble250 mg plus 5 ml of solvent, clear, colorless to faintly yellow
- form
- Off-white solid
- color
- White to Almost white
- Water Solubility
- Soluble in water (75 mM), DMSO (100 mM), chloroform, ethanol, and methanol.
- Sensitive
- Light Sensitive & Hygroscopic
- λmax
- 317nm(EtOH)(lit.)
- Merck
- 14,9359
- InChIKey
- NZFNXWQNBYZDAQ-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P501
- Hazard Codes
- Xn,N
- Risk Statements
- 22-36/37/38-50/53
- Safety Statements
- 26-36-60-61
- RIDADR
- UN 3077 9/PG 3
- WGK Germany
- 3
- RTECS
- SP2275000
- HazardClass
- 9
- HS Code
- 2934302300
Use
Thioridazine hydrochloride,10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine monohydrochloride (Mellaril), is amember of the piperidine subgroup of the phenothiazines.The drug has a relatively low tendency to produce EPS. Thedrug has high anticholinergic activity, and this activity in thestriatum, counterbalancing a striatal DA block, may be responsiblefor the low EPS. It also has been suggested thatthere may be increased DA receptor selectivity, which may be responsible. The drug has sedative and hypotensive activityin common with chlorpromazine and less antiemeticactivity. At high doses, pigmentary retinopathy has been observed.Its major metabolites include N-demethylated, ringhydroxylated,and S-oxidized products. Thioridazine isprominently converted to the active metabolite mesoridazine(discussed next), which probably contributes to the antipsychoticactivity of thioridazine.
8 India supplier list of "Thioridazine hydrochloride"
- Product Name:Thioridazine hydrochloride
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Thioridazine hydrochloride
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Thioridazine Hcl
- Products Intro:Purity: 99% | Package: Kg to Mtons
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Thioridazine hydrochloride
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:DopamineReceptorAntagonistII,Thioridazine,HCl-CAS130-61-0-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:324387 | Purity:TheDopamineReceptorAntagonistII,Thioridazine,HCl,alsoreferencedunderCAS130-61-0,
- Company Type: Trader
- Country/Region: INDIA