Valsartan
Valsartan
- CAS:
- 137862-53-4
- MF:
- C24H29N5O3
- MW:
- 435.52
Suppliers by country/region
- India(215)
- Singapore(1)
- CHINA(355)
- United States(84)
- United Kingdom(25)
- Canada(13)
- Germany(14)
- Sweden(2)
- Europe(3)
- Japan(3)
- Philippines(1)
- Mexico(2)
- Slovenia(2)
- South Korea(18)
- Israel(1)
- France(4)
- Ukraine(1)
- Italy(2)
- Belgium(1)
- Indonesia(1)
- Brazil(4)
- Bangladesh(1)
- The Netherlands(1)
- Uruguay(1)
- South Africa(1)
- Greece(1)
- Colombia(1)
- Austria(1)
- Switzerland(2)
- Spain(3)
- Argentina(1)
- Poland(1)
- Nepal(1)
- Iran(2)
- Malaysia(1)
- Egypt(1)
- United Arab Emirates(1)
Company Type
Properties
- Melting point:
- 116-117°C
- Boiling point:
- 684.9±65.0 °C(Predicted)
- Density
- 1.212±0.06 g/cm3(Predicted)
- vapor pressure
- 0-0Pa at 20-25℃
- storage temp.
- 2-8°C
- solubility
- DMSO: ≥20mg/mL
- form
- powder
- pka
- 3.56±0.10(Predicted)
- color
- white to tan
- optical activity
- [α]/D -55 to -70°, c = 1 in methanol
- Water Solubility
- 84.99mg/L(25 ºC)
- Merck
- 14,9916
- BCS Class
- 2
- Stability:
- Hygroscopic
- InChIKey
- ACWBQPMHZXGDFX-QFIPXVFZSA-N
- LogP
- 1.2-2.8 at 25℃ and pH2.5-7
- Surface tension
- 59.6-68.1mN/m at 10-100mg/L and 20℃
- Dissociation constant
- 3.76-4.38 at 25℃
Safety Information
- Symbol(GHS)
GHS07,GHS08
- Signal word
- Warning
- Hazard statements
- H336-H361d
- Precautionary statements
- P201-P308+P313
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-37/39
- WGK Germany
- 3
- RTECS
- YV9455000
- HS Code
- 29339900
Use
Valsartan selectively affects the AT1 receptor subtype and prevents AT1 from binding with AT1 receptors (its selective AT1 receptor antagonizing effect is about 20000 times greater than its effects on AT2 receptors), thus inhibiting vasoconstriction and aldosterone release, producing an antihypertensive effect, but it cannot inhibit the release of aldosterone caused by potassium ions (K+). Valsartan does not affect angiotensin-converting enzymes (ACE) or renin and its receptors, and it does not inhibit ion channels related to blood pressure regulation and sodium balance. Valsartan does not inhibit ACE and does not affect bodily bradykinin levels, thus causing less coughing side effects than ACE inhibitors. Valsartan does not affect heart rate when lowering blood pressure. Sudden ceasing in Valsartan use will not cause rebound hypertension or other side effects. Valsartan does not affect hypertension patients overall cholesterol, triglyceride, blood glucose, or uric acid levels.
215 India supplier list of "Valsartan"
![](/images/pro-3.jpg)
- Product Name:Valsartan API
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
![](/images/pro-3.jpg)
- Product Name:Valsartan
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
![](/images/pro-3.jpg)
- Product Name:VALSARTAN
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
![](/images/pro-3.jpg)
- Product Name:Valsartan
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
![](/images/pro-3.jpg)
- Product Name:Valsartan
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: INDIA
![](/images/pro-3.jpg)
- Product Name:Valsartan
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: INDIA
![](/images/pro-3.jpg)
- Product Name:Valsartan
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1MT
- Company Type: Manufacturer
- Country/Region: INDIA
![](/images/pro-3.jpg)
- Product Name:Valsartan
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
![](/images/pro-3.jpg)
- Product Name:Valsartan
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA