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VX-745

VX-745

CAS:
209410-46-8
MF:
C19H9Cl2F2N3OS
MW:
436.26

Properties

Melting point:
261-264 °C
Boiling point:
578.9±60.0 °C(Predicted)
Density 
1.55±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
≥21.8 mg/mL in DMSO; insoluble in H2O; ≥2.1 mg/mL in EtOH with gentle warming and ultrasonic
form 
powder
pka
-0.97±0.40(Predicted)
color 
white to beige

Safety Information

Symbol(GHS) 

GHS07
Signal word 
Warning
Hazard statements 
H302-H315-H319-H332-H335
Precautionary statements 
P261-P280-P305+P351+P338
HS Code 
2933599590

Use

VX 745 is a potent and selective inhibitor of p38α mitogen-activated protein (MAP) kinase. VX 745 is a potential anti-inflammatory agents. Studies suggest that VX 745 may be useful in the treatment of Werner syndrome.

1 India supplier list of "VX-745"

  • Product Name:VX-745
  • Products Intro:Brand:sigma aldrich | Product Number:SML1638 | Purity:≥98%(HPLC)
  • Company Type: Trader
  • Country/Region: Bangalore,INDIA
  • Product Name:VX745 >95%
  • Products Intro:Brand:Glrinnovations | OriginalID:GLR19.089154
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:VX745
  • Products Intro:Brand:clearsynth | Product Number:CS-T-46562
  • Company Type: Trader
  • Country/Region: Hyderabad,INDIA
  • Product Name:VX-745
  • Products Intro:Brand:ajchemicals | Product Number:JDH-38471 | Purity:98+%
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:5-(2,6-dichlorophenyl)-2-(2,4-difluorophenylthio)-6H-pyrimido[1,6-b]pyridazin-6-one
  • Products Intro:Purity: 98%(Min,HPLC) | Package: 100g;1kg;5kg,10kg,25kg,50kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: 1159983-30-8,89466-59-1,149739-51-5,104901-79-3,10541-83-0
  • Product Name:VX-745
  • Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
  • Company Type: Reagent
  • Country/Region: CHINA
  • Product Name:vx-745
  • Products Intro:Purity: 0.99 | Package: 1kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:VX-745
  • Products Intro:Purity: 99% | Package: 100g,1kg | CustNote: API
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: drug intermediates,organic photoeletric materials,hybrid compounds,pharmaceuticals
  • Product Name:5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido(1,6-b)pyridazin-6-one
  • Products Intro:Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Factory Supply
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Neflamapimod VX-745 MAPK inhibitor
  • Products Intro:Purity: 99% | Package: 5KG;1KG
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: sarms

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