Citarinostat
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- $36 - $2839
- Product name: Citarinostat
- CAS: 1316215-12-9
- MF: C24H26ClN5O3
- MW: 467.95
- EINECS:
- MDL Number:MFCD28023593
- Synonyms:2-[(2-Chlorophenyl)phenylamino]-N-[7-(hydroxyamino)-7-oxoheptyl]-5-pyrimidinecarboxamide;Citarinostat;Citarinostat (ACY-241);ACY-241(CITARINOSTAT);2-((2-Chlorophenyl)(phenyl)aMino)-N-(7-(hydroxyaMino)-7-oxoheptyl)pyriMidine-5-carboxaMide;5-Pyrimidinecarboxamide, 2-[(2-chlorophenyl)phenylamino]-N-[7-(hydroxyamino)-7-oxoheptyl]-;HDAC-IN-2;Citarinostat(ACY-241,HDAC-IN-2)
28 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 2x10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberX3978
- Product descriptionHDAC-IN-2
- Packaging2mg
- Price$128
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX3978
- Product descriptionHDAC-IN-2
- Packaging5mg
- Price$151
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX3978
- Product descriptionHDAC-IN-2
- Packaging25mg
- Price$266
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA207811
- Product description2-((2-Chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide 98+%
- Packaging1mg
- Price$36
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA207811
- Product description2-((2-Chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide 98+%
- Packaging5mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA207811
- Product description2-((2-Chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide 98+%
- Packaging10mg
- Price$78
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA207811
- Product description2-((2-Chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide 98+%
- Packaging50mg
- Price$132
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA207811
- Product description2-((2-Chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide 98+%
- Packaging100mg
- Price$172
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA207811
- Product description2-((2-Chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide 98+%
- Packaging250mg
- Price$337
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA207811
- Product description2-((2-Chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide 98+%
- Packaging1g
- Price$843
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5936
- Product descriptionACY-241
- Packaging5mg
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5936
- Product descriptionACY-241
- Packaging25mg
- Price$399
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon3039
- Product descriptionACY-241-Citarinostat 98%
- Packaging2x10mg
- Price$198
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573249
- Product descriptionCitarinostat(ACY-241) >98%
- Packaging100mg
- Price$765
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573249
- Product descriptionCitarinostat(ACY-241) >98%
- Packaging250mg
- Price$1431.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573249
- Product descriptionCitarinostat(ACY-241) >98%
- Packaging1g
- Price$2839
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | X3978 | HDAC-IN-2 | 2mg | $128 | 2021-12-16 | Buy |
| AK Scientific | X3978 | HDAC-IN-2 | 5mg | $151 | 2021-12-16 | Buy |
| AK Scientific | X3978 | HDAC-IN-2 | 25mg | $266 | 2021-12-16 | Buy |
| Ambeed | A207811 | 2-((2-Chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide 98+% | 1mg | $36 | 2021-12-16 | Buy |
| Ambeed | A207811 | 2-((2-Chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide 98+% | 5mg | $60 | 2021-12-16 | Buy |
| Ambeed | A207811 | 2-((2-Chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide 98+% | 10mg | $78 | 2021-12-16 | Buy |
| Ambeed | A207811 | 2-((2-Chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide 98+% | 50mg | $132 | 2021-12-16 | Buy |
| Ambeed | A207811 | 2-((2-Chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide 98+% | 100mg | $172 | 2021-12-16 | Buy |
| Ambeed | A207811 | 2-((2-Chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide 98+% | 250mg | $337 | 2021-12-16 | Buy |
| Ambeed | A207811 | 2-((2-Chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide 98+% | 1g | $843 | 2021-12-16 | Buy |
| ApexBio Technology | B5936 | ACY-241 | 5mg | $147 | 2021-12-16 | Buy |
| ApexBio Technology | B5936 | ACY-241 | 25mg | $399 | 2021-12-16 | Buy |
| Axon Medchem | Axon3039 | ACY-241-Citarinostat 98% | 2x10mg | $198 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573249 | Citarinostat(ACY-241) >98% | 100mg | $765 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573249 | Citarinostat(ACY-241) >98% | 250mg | $1431.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573249 | Citarinostat(ACY-241) >98% | 1g | $2839 | 2021-12-16 | Buy |
Properties
Density :1.293±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥23.4 mg/mL in DMSO; insoluble in H2O; ≥4.87 mg/mL in EtOH with ultrasonic
form :solid
pka :9.47±0.20(Predicted)
color :White to off-white
storage temp. :Store at -20°C
solubility :≥23.4 mg/mL in DMSO; insoluble in H2O; ≥4.87 mg/mL in EtOH with ultrasonic
form :solid
pka :9.47±0.20(Predicted)
color :White to off-white
Safety Information
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Description
ACY-241 is an inhibitor of histone deacetylase 6 (HDAC6; IC50 = 2.6 nM). It is selective for HDAC6 over HDAC1-3, HDAC7, and HDAC9 (IC50s = 35, 45, 46, 7,300, and 137 nM, respectively), as well as HDAC4, HDAC5, and HDAC9 (IC50 = >20,000 nM for all). It reduces proliferation of A2780, TOV-21G, and MDA-MB-231 cells when used at a concentration of 3 μM and completely inhibits it and induces apoptosis at a concentration of 10 μM. ACY-241, when used in combination with paclitaxel , inhibits proliferation in MiaPaCa-2, TOV-21G, and T47D cells. It also reduces tumor growth in a MiaPaCa-2 mouse xenograft model when administered at a dose of 50 mg/kg in combination with paclitaxel. ACY-241, in combination with the somatostatin receptor agonist pasireotide , reduces hepatorenal cystogenesis in a rat model of polycystic liver disease.More related product prices
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