DMT-2μ-O-Me-rG(ib) amidite manufacturers
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| | DMT-2μ-O-Me-rG(ib) amidite Basic information |
| Product Name: | DMT-2μ-O-Me-rG(ib) amidite | | Synonyms: | DMT-2μ-O-Me-rG(ib) amidite;5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine 3'-CE phosphoramidite;Guanosine, 5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-O-(2-Methoxyethyl)-N-(2-Methyl-1-oxopropyl)-, 3'-[2-cyanoethyl bis(1-Methylethyl)phosphoraMidite];2'-MOE-G(iBu)-3'-phosphoramidite;5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite];5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O-methylguanosine-3'-(2-cyanoethyl diisopropylphosphoramidite);GUANOSINE, 5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-(2-METHOXYETHYL)-N-(2-METHYL-1-OXOPROPYL)-, 3'-[2-CYANOETHYL BIS(1-METHYLETHYL)PHOSPHORAMIDITE] (9CI);2'-O-MOE-ibu-G Phosphoramidite | | CAS: | 251647-55-9 | | MF: | C47H60N7O10P | | MW: | 913.99 | | EINECS: | | | Product Categories: | RNA Amidites;Sigma-Proligo;2-Methyl RNA STD Amidites;Amidite | | Mol File: | 251647-55-9.mol |  |
| | DMT-2μ-O-Me-rG(ib) amidite Chemical Properties |
| storage temp. | 4°C, protect from light | | solubility | DMSO : 250 mg/mL (273.53 mM; Need ultrasonic) | | form | Powder | | pka | 9.16±0.20(Predicted) | | color | White to Off-white | | InChIKey | LADCDGNEBIQAAU-KEFUZROQNA-N |
| | DMT-2μ-O-Me-rG(ib) amidite Usage And Synthesis |
| Description |
Nucleoside phosphoramidites are used in the synthesis of oligonucleotides. Using a chemical approach allows quick and inexpensive access to custom-made oligonucleotides of the desired sequence. Enzymatic synthesis proceeds in a 5’ to 3’ direction, however the chemical synthesis is usually performed in the opposite direction. 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite, also known as DMT-2μ-O-Me-rG(ib) amidite, is a modified guanosine with a 2’-O-(2-methoxyethyl) group, these have been used in the synthesis of oligonucleotides as antisense drugs.
| | Uses | 5''-O-DMT-N2-isobutyryl-2''-O-(2-methoxyethyl)-guanosine 3''-CE phosphoramidite (CAS# 251647-55-9) is a nucleotide, and a derivative of guanosine, and is used in the stereochemical sythesis of phosphorothioate oligonucleotides. | | storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| | DMT-2μ-O-Me-rG(ib) amidite Preparation Products And Raw materials |
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