Temocapril hydrochloride
Temocapril hydrochloride атрибут
| Температура плавления: |
196-2000C (dec) |
| альфа: |
25D +47.7° (c = 1 in DMF) |
| температура хранения: |
Inert atmosphere,Store in freezer, under -20°C |
| растворимость: |
ДМФ (немного), ДМСО (немного), метанол (немного) |
| форма: |
Твердый |
| цвет: |
От белого до не совсем белого |
| Справочник по базе данных CAS: |
110221-44-8(CAS DataBase Reference) |
| FDA UNII: |
8G820I95VP |
Заявления о рисках и безопасности
| Коды опасности |
Xi |
| Заявления о рисках |
36/37/38 |
| Заявления о безопасности |
26-36 |
| Токсичность |
LD50 in mice, rats, dogs (mg/kg): >5000, >5000, >800 orally (Koike) |
Temocapril hydrochloride химические свойства, назначение, производство
Описание
Temocapril is a novel ACE inhibitor marketed in Japan for the treatment of
hypertension. Temocapril is three times more potent than enalapril by oral
administration, and has a long duration of action. It is characterized by a rapid onset
of action resulting from a fast conversion of temocapril to the active metabolite
diacid. Unlike most ACE inhibitors which are excreted mainly through the kidneys,
temocapril is excreted predominantly through the biliary route indicating that
temocapril is especially useful for treating hypertensive patients with renal
dysfunction. The potential usefulness of temocapril in the treatment of congestive
heart failure has been reported.
Химические свойства
White To Off-White Solid
Temocapril hydrochloride препаратная продукция и сырье
сырьё
препарат
Temocapril hydrochloride поставщик
Global( 148)Suppliers
110221-44-8()подобный поиск: