Фамотидин химические свойства, назначение, производство
Описание
Famotidine is a competitive histamine H2-receptor antagonist, and the main pharmacodynamic
effect of famotidine is to cause the inhibition of gastric secretion. Famotidine on
decomposition releases toxic products such as carbon oxides (CO, CO2), nitrogen oxides (NO, NO2), and sulphur oxides (SO2, SO3). Famotidine is a medication that is available both
in prescription and over-the-counter forms. It is used to treat conditions related to the
oesophagus, stomach, and intestines. Some specific famotidine is used for the treatment of
duodenal ulcers, gastric ulcers (stomach ulcers), gastroesophageal reflux disease (GERD),
and pathological hypersecretory conditions that occur when stomach acid is secreted/
produced in very large quantities, an abnormal health condition called ‘Zollinger-Ellison
syndrome’.
Химические свойства
White Powder
Использование
Contact dermatitis from famotidine, a H2 -receptor
agonist, was described in a nurse. In industry, three
cases were reported due to intermediates of synthesis, 2-
diamino-ethylene-amino-thiazolyl-methylenethiourea-dichloride
and 4-chloromethyl-2-guanidinothiazolenitrochloride.
Общее описание
Famotidine is a histamine H2-receptor antagonist, which promotes the healing of erosive esophagitis, gastric and duodenal ulcers since it inhibits the gastric acid secretion in humans.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Контактные аллергены
Contact dermatitis in a nurse from famotidine, an
H2-receptor agonist, was described. In industry, three
cases were reported due to intermediates of the synthesis
of 2-diamino-ethylene-amino-thiazolyl-methylenethio urea-dichloride, and 4-chloromethyl-2-guanidinothiaz ole-nitrochloride.
Клиническое использование
Famotidine is a histamine H2-antagonist more potent than cimetidine and
ranitidine. Administered once or twice daily, it is useful in the treatment of
gastric, duodenal and anastomotic ulcers, upper gastrointestinal tract hemorrhage,
reflux esophagitis and Zollinger-Ellison syndrome. Like ranitidine, it is lacking in
antiandrogenic effects.
Фамотидин препаратная продукция и сырье
сырьё
препарат