Imazapyr acid
Imazapyr acid атрибут
Температура плавления: |
169-173°C |
Температура кипения: |
404.53°C (rough estimate) |
плотность: |
1.1923 (rough estimate) |
давление пара: |
0-0Pa at 20-25℃ |
показатель преломления: |
1.5600 (estimate) |
температура хранения: |
0-6°C |
пка: |
1.9, 3.6(at 25℃) |
БРН: |
5442754 |
Стабильность:: |
Стабильный. Несовместим с сильными окислителями. |
LogP: |
-3.97-0.04 at 20℃ and pH3-9.9 |
Dissociation constant: |
1.7-11.1 at 20℃ |
Справочник по базе данных CAS: |
81334-34-1(CAS DataBase Reference) |
FDA UNII: |
787MX0M5A6 |
Система регистрации веществ EPA: |
Imazapyr (81334-34-1) |
безопасность
- Заявления о рисках и безопасности
- код информации об опасности(GHS)
Коды опасности |
Xi |
Заявления о рисках |
36-52/53 |
Заявления о безопасности |
26-61 |
WGK Германия |
2 |
RTECS |
US5682500 |
кода HS |
29333990 |
Банк данных об опасных веществах |
81334-34-1(Hazardous Substances Data) |
Токсичность |
LD50 orally in rats: >5000 mg/kg; dermally in rabbits: >2000 mg/kg (Paxman) |
символ(GHS) |
|
сигнальное слово |
Warning |
Заявление об опасности |
пароль |
Заявление об опасности |
Класс опасности |
категория |
сигнальное слово |
пиктограмма |
предупреждение |
H319 |
При попадании в глаза вызывает выраженное раздражение. |
Серьезное повреждение/раздражение глаз |
Категория 2А |
Предупреждение |
![](/GHS07.jpg) |
P264, P280, P305+P351+P338,P337+P313P |
|
Внимание |
P264 |
После работы тщательно вымыть кожу. |
P280 |
Использовать перчатки/ средства защиты глаз/ лица. |
P305+P351+P338 |
ПРИ ПОПАДАНИИ В ГЛАЗА: Осторожно промыть глаза водой
в течение нескольких минут. Снять контактные линзы, если
Вы ими пользуетесь и если это легко сделать. Продолжить
промывание глаз. |
P337+P313 |
Если раздражение глаз не проходит обратиться за
медицинской помощью. |
|
Imazapyr acid химические свойства, назначение, производство
Химические свойства
solid
Использование
Imazapyr is an analytical standard used for proteomics research.
Фармаколо?гия
Imazapyr kills plants by inhibiting acetolactate synthase
(ALS) (I50 = 5 μM), which is the first common enzyme in
the biosynthesis of the branched chain amino acids, valine,
leucine, and isoleucine. Imazapyr is rapidly absorbed
through the leaves of plants. Once it enters the plant,
imazapyr rapidly translocates to the growing points and
growth ceases within 1 day after herbicide application
followed by chlorosis and then necrosis of the growing
points. Total plant death will occur within 2 to 3 weeks
after treatment.
Экологическая судьба
Imazapyr is weakly to moderately adsorbed on sandy loam
and silt loam soils. The Freundlich adsorption coefficient ranges from 0 to 7.8 (15). Because imazapyr is a weak acid
and exists in different ionic states, soil pH has an effect on
soil binding properties. The anionic form predominates at
soil pH as low as 5.5, and this form bindsweakly to soil. The
neutral or molecular form is important at soil pH from 4
to 6.5. This form binds to soil organic matter and clay. The
cationic form is important at pH less than 4. Because the
soil is a heterogeneous mixture of acid and base chemical
groups, there may be sites within a particular soil that are
2 to 3 pH units higher or lower than the average pH. The
cationic form will bind tightly to the lower pH components.
Because of these interactions, small decreases in pH below 6 will result in large increases in binding. The half-life of
imazapyr in the soil is 25–142 d (14). Imazapyr remains
in the top 30 cm of the soil with low leaching potential.
The degradation route of imazapyr in the soil has not been
determined.
Метаболизм
Plant Metabolism. The selectivity of imazapyr is due to
differential rates and routes of metabolism in tolerant
crops versus susceptible weeds (3). The half-life
of imazapyr in tolerant crops has not been accurately
determined. The metabolic route of imazapyr is not clear.
The parent compound can be metabolized to a tricyclic
compound (33, Fig. 15) in some species, but the primary
metabolite is an imidazopyrrolo-pyridine derivative (34,
Fig. 15). This compound does not inhibit acetolactate
synthase, the target site for the imidazolinones, and it
is immobile in the plant (4).
Animal Metabolism. Metabolism studies in the rat
showed that imazapyr is rapidly excreted in the urine (5).
There was no accumulation of imazapyr or any of its
derivatives in the liver, kidney, muscle, fat, or blood.
Imazapyr acid препаратная продукция и сырье
сырьё
препарат
Imazapyr acid поставщик
Global( 142)Suppliers
81334-34-1()подобный поиск: