Холевая кислота
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81-25-4
|
- CAS №
- 81-25-4
- Химическое название:
- Холевая кислота
- английское имя:
- Cholic acid
- Синонимы:
- CA;CHOLATE;cholan-24-oic acid;3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid;3A,7A,12A-TRIHYDROXY-5B-CHOLAN-24-OIC ACID;(R)-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-diMethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid;CHOLALIN;Cholicaci;Cholic acd;CHOLIC ACID
- CBNumber:
- CB9263222
- Формула:
- C24H40O5
- молекулярный вес:
- 408.58
- MOL File:
- 81-25-4.mol
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Холевая кислота атрибут
| Температура плавления: |
200-201 °C (lit.) |
| Температура кипения: |
449.08°C (rough estimate) |
| альфа: |
36 º (c=0.6, 95% EtOH) |
| плотность: |
1.0310 (rough estimate) |
| показатель преломления: |
1.5800 (estimate) |
| Fp: |
9℃ |
| температура хранения: |
2-8°C |
| растворимость: |
метанол: 0,1 г/мл, прозрачный |
| пка: |
4.98(at 20℃) |
| форма: |
Solid |
| цвет: |
От белого до коричневого |
| Растворимость в воде: |
0,28 г/л (15°С) |
| Мерк: |
14,2203 |
| БРН: |
2822009 |
| ИнЧИКей: |
BHQCQFFYRZLCQQ-OELDTZBJSA-N |
| LogP: |
2.03-2.615 at 20℃ |
| Справочник по базе данных CAS: |
81-25-4(CAS DataBase Reference) |
| Вещества, добавляемые в пищу (ранее EAFUS): |
CHOLIC ACID |
| Специальный комитет по веществам GRAS: |
Cholic acid |
| Рейтинг продуктов питания EWG: |
1 |
| FDA UNII: |
G1JO7801AE |
| Код УВД: |
A05AA03 |
| Справочник по химии NIST: |
Cholic acid(81-25-4) |
| Система регистрации веществ EPA: |
Cholan-24-oic acid, 3,7,12-trihydroxy-, (3.alpha.,5.beta.,7.alpha.,12.alpha.)- (81-25-4) |
Холевая кислота химические свойства, назначение, производство
Химические свойства
white to light beige crystalline powder
Использование
Cholic Acid is an emulsifier that exists as colorless plates or a white
crystalline powder which has a bitter taste with a sweetish aftertaste.
it is slightly soluble in water. it functions as an emulsifying agent in
egg white.
Определение
ChEBI: A bile acid that is 5beta-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12.
Общее описание
This Certified Spiking Solution? is suitable as a starting material in preparation of linearity standards, calibrators, and controls for use in LC-MS/MS and GC/MS bile acid testing methods. Cholic acid is a primary bile acid that plays an important role in cholesterol homeostasis and intestinal absorption of dietary vitamins and lipids. Levels of cholic acid can serve as markers for inborn and acquired hepatobiliary disorders such as biliary atresia and familial intrahepatic cholestasis as well as inborn errors of bile acid synthesis and sclerosing cholangitis.
Методы очистки
This bile acid crystallises from H2O or wet Et2O (as hydrate) or EtOH (as alcoholate). Dry it under vacuum at 94o. When an alcoholic solution of cholic acid + I2 is added to aqueous KI, it forms a molecular compound (C24H40O5I)4 KI. H2O. The methyl ester is dimorphic with m 155o and 162o and [] D 20 +25o (EtOH). [Anderson et al. Biochem J 67 323 1957, 85 236 1962, Beilstein 10 III 2162, IV 2071.]
Холевая кислота препаратная продукция и сырье
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Холевая кислота поставщик
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