4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE
4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE
![4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE](/CAS/GIF/101574-65-6.GIF)
- CAS:
- 101574-65-6
- MF:
- C17H18N2O2
- MW:
- 282.34
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Company Type
Properties
- Density
- 1.12
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- DMSO: >10mg/mL
- form
- powder
- pka
- 8.48±0.15(Predicted)
- color
- white to off-white
Safety Information
- Symbol(GHS)
GHS07,GHS09
- Signal word
- Warning
- Hazard statements
- H317-H410
- Precautionary statements
- P261-P272-P273-P280-P302+P352-P333+P313
- Hazard Codes
- Xi,N
- Risk Statements
- 43-50/53
- Safety Statements
- 36/37-60-61
- RIDADR
- UN 3077 9 / PGIII
- WGK Germany
- 3
- HazardClass
- 9
Use
The estrogen-related receptors (ERRs) are orphan nuclear receptors with homology to the estrogen receptor family and are expressed in tissues with high metabolic demand. Binding of peroxisome proliferator-activated receptor γ-coactivator 1α (PGC-1α) to this class of receptors is known to potentiate ERR activity. GSK4716 is an ERRβ/γ agonist (IC50 = 2 μM) that can activate the receptor with similar potency as the protein ligand, PGC-1α. It is more than 50-fold selective for binding to ERRβ/γ compared with the estrogen receptors. This compound has been used to demonstrate the contribution of ERR receptor activity to the regulation of mitochondrial activity in skeletal muscle during exercise.[Cayman Chemical]
0 India supplier list of "4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE"
- Product Name:GSK4716
- Products Intro:Brand:sigma aldrich | Product Number:G6173 | Purity:≥98%(HPLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Gsk4716
- Products Intro:Brand:ajchemicals | Product Number:JDH-83945 | Purity:95%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:GSK4716
- Products Intro:Brand:clearsynth | Product Number:CS-T-78234
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:GSK 4716
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE
- Products Intro:Purity: 98% | Package: 1KG;1USD|1KG;1USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
$1.00-1.00 / 1KG
- Product Name:4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE
- Products Intro:Purity: 0.98 | Package: 1kg，2kg，5kg，10kg，25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL
- Product Name:4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE
- Company Type: Trader
- Country/Region: CHINA
- Product Name:4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE
- Products Intro:Purity: 95% | Package: 500Mg ;1g;2.5g ;5g ;10g
- Company Type: Trader
- Country/Region: CHINA
- Main Products: pharmaceuticals,OLEDs,material intermediates
- Product Name:GSK 4716
- Products Intro:Package: 1g; 5g; 25g; 1kg; 5kg; 25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmaceutical intermediate
- Product Name:GSK 4716
- Products Intro:Purity: 98% | Package: $47.9/5mg;$77.9/10mg;$175.9/25mg;$338.9/50mg;$599.9/100mg;Bulk package | CustNote: 98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies