5-Azacytidine
5-Azacytidine
- CAS:
- 320-67-2
- MF:
- C8H12N4O5
- MW:
- 244.2
Suppliers by country/region
Company Type
Properties
- Melting point:
- 226-232 °C (dec.)(lit.)
- Boiling point:
- 387.12°C (rough estimate)
- alpha
- 40 º (C=1, H2O 22 ºC)
- Density
- 1.4287 (rough estimate)
- refractive index
- 1.6590 (estimate)
- storage temp.
- -20°C
- solubility
- Soluble in DMSO (up to 25 mg/ml), or in Water (up to 12 mg/ml).
- form
- lyophilized powder
- pka
- 13.46±0.70(Predicted)
- color
- White to Off-white
- Water Solubility
- 0.5-1.0 g/100 mL at 21 ºC
- Merck
- 14,887
- BRN
- 620461
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
- InChIKey
- NMUSYJAQQFHJEW-WGDKFINWSA-N
- LogP
- -2.191 (est)
Safety Information
- Symbol(GHS)
GHS07,GHS08,GHS09
- Signal word
- Danger
- Hazard statements
- H302-H341-H350-H360FD-H372-H410
- Precautionary statements
- P202-P260-P264-P273-P301+P312-P308+P313
- Hazard Codes
- T
- Risk Statements
- 45-46-22
- Safety Statements
- 53-22-36/37/39-45
- WGK Germany
- 3
- RTECS
- XZ3017500
- F
- 10-23
- HS Code
- 29349990
- Toxicity
- LD50 in mice (mg/kg): 115.9 i.p.; 572.3 orally (Palm, Kensler)
Use
5-Azacytidine is an analog of the nucleoside cytidine which can be incorporated into DNA and RNA. 5-Azacytidine acts as an epigenetic modifier by incorporating into DNA where it irreversibly binds to DNA methyltransferases, thus inhibiting their activity.
65 India supplier list of "5-Azacytidine"
- Product Name:5-Azacytidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:5-Azacytidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:5-Azacytidine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Azacitidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:5-Azacytidine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:5-Azacytidine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:AZACITIDINE
- Products Intro:Purity: 95-99% | Package: 1-5 gm, the rest upon order
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:5-Azacytidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:5-Azacytidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:5-Azacytidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA