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Bupropion
Bupropion
- CAS:
- 34911-55-2
- MF:
- C13H18ClNO
- MW:
- 239.74
Properties
- Melting point:
- 233-234°C
- Boiling point:
- bp.005 52°
- Density
- 1.066±0.06 g/cm3(Predicted)
- solubility
- ethanol: 193 mg/mL solutions may be stored for several days at 4 °C.
- form
- solid
- pka
- pKa 7.0 (Uncertain)
- color
- white
- BCS Class
- 1
Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 22
- Safety Statements
- 36
- WGK Germany
- 3
- RTECS
- UG8858000
- HazardClass
- IRRITANT
Use
Bupropion hydrochloride, an aminoketone structurally unrelated to tricyclics or tetracyclics, is a dopamine uptake blocker with antidepressant activity. Its clinical efficacy is reportedly comparable to that of amitriptyline, yet unlike most conventional antidepressants, bupropion hydrochloride is not associated with orthostatic hypotension or other cardiovascular side-effects.
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