Cephalexin
Cephalexin
- CAS:
- 15686-71-2
- MF:
- C16H17N3O4S
- MW:
- 347.39
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Properties
- Melting point:
- 196-198°C
- alpha
- [α]D20 +144～+158° (c=0.5, H2O) (Calculated on dehydrous basis)
- Boiling point:
- 727.4±60.0 °C(Predicted)
- Density
- 1.3040 (rough estimate)
- refractive index
- 1.6320 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- NH4OH 1 M: 50 mg/mL, clear, yellow
- form
- Solid
- pka
- 5.2, 7.3(at 25℃)
- color
- White to light yellow
- PH
- pH (5g/l, 25℃) 3.5～5.5
- Water Solubility
- 12.5g/L(25 ºC)
- Merck
- 13,1986
- BCS Class
- 4
- InChIKey
- AVGYWQBCYZHHPN-CYJZLJNKSA-N
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Danger
- Hazard statements
- H317-H334
- Precautionary statements
- P261-P272-P280-P284-P302+P352-P333+P313
- Hazard Codes
- Xn
- Risk Statements
- 42/43
- Safety Statements
- 22-36/37-45
- WGK Germany
- 3
- RTECS
- XI0350000
- HS Code
- 29419000
- Toxicity
- TDLo orl-hmn: 14 mg/kg/D:GIT AACHAX -,361,68
Use
Cephalexin, 7α-(D-amino-α-phenylacetamido)-3-methylcephemcarboxylicacid (Keflex, Keforal), was designed purposelyas an orally active, semisynthetic cephalosporin. Theoral inactivation of cephalosporins has been attributed to twocauses: instability of the β-lactam ring to acid hydrolysis(cephalothin and cephaloridine) and solvolysis or microbialtransformation of the 3-methylacetoxy group (cephalothin,cephaloglycin). The α-amino group of cephalexin renders itacid stable, and reduction of the 3-acetoxymethyl to a methylgroup circumvents reaction at that site.Cephalexin occurs as a white crystalline monohydrate. Itis freely soluble in water, resistant to acid, and absorbed wellorally. Food does not interfere with its absorption. Becauseof minimal protein binding and nearly exclusive renal excretion,cephalexin is recommended particularly for the treatmentof urinary tract infections. It is also sometimes used forupper respiratory tract infections. Its spectrum of activity isvery similar to those of cephalothin and cephaloridine.Cephalexin is somewhat less potent than these two agentsafter parenteral administration and, therefore, is inferior tothem for the treatment of serious systemic infections.
53 India supplier list of "Cephalexin"
- Product Name:Cephalexin
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Cephalexin
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Cephalexin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Haryana,INDIA
- Product Name:Cephalexin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Cephalexin
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Cephalexin
- Products Intro:Purity: 98% | Package: 25mg; 50mg; 100mg; Customised
- Company Type: Trader
- Country/Region: Punjab,INDIA
- Product Name:Cephalexin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Cephalexin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Cefalexin
- Products Intro:Brand:sigma aldrich | Product Number:33989 | Purity:VETRANAL?,analyticalstandard
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Cephalexin 98.00%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.030678
- Company Type: Trader
- Country/Region: New Delhi,INDIA