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α-Lipoic Acid

α-Lipoic Acid

CAS:
1077-28-7
MF:
C8H14O2S2
MW:
206.33

Properties

Melting point:
60-62 °C
Boiling point:
160-165 °C(lit.)
Density 
1.2888 (rough estimate)
refractive index 
1.5200 (estimate)
Flash point:
160-165°C
storage temp. 
2-8°C
solubility 
ethanol: 50 mg/mL
pka
4.75±0.10(Predicted)
form 
Crystals or Crystalline Powder
color 
Yellow
Water Solubility 
0.9 g/L (20 ºC)
Merck 
14,9326
BRN 
81853
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
AGBQKNBQESQNJD-UHFFFAOYSA-N
LogP
2.530 (est)

Safety Information

Symbol(GHS) 

GHS07,GHS09
Signal word 
Warning
Hazard statements 
H302-H315-H317-H319-H411
Precautionary statements 
P261-P273-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes 
Xn
Risk Statements 
22-20/21/22
Safety Statements 
37/39-26-24/25-36-36/37/39
WGK Germany 
3
RTECS 
JP1192000
HS Code 
29349990

Use

Lipoic acid(ALA), also known as α-lipoic acid (alpha-lipoic acid) or thioctic acid, has the formula C8H14S2O2 and systematic name 5-(1,2-dithiolan-3-yl)pentanoic acid. It contains a disulfide group, which can be transformed in the body to a dithiol group. ALA has been on the market since the 1950s as a dietary supplement. It is a natural antioxidant usually made by the body. The advantage of ALA over other antioxidants such as vitamin C and E is that it is soluble both in water and in fat. Researchers in the former Soviet Union found that ALA can chelate mercury once it is transformed into the dithiol-containing compound. ALA can penetrate both the blood–brain barrier and the cell membrane and therefore would be a very interesting chelating agent. Nevertheless, there is much debate about its mode of action, side effects and effectiveness. Other antidotes, such as BAL and DMSA, are more efficient in the removal of heavy metals. ALA has not received FDA approval as a chelating agent, but it is still sold as a food supplement.

88 India supplier list of "α-Lipoic Acid"

  • Product Name:Thioctic acid
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Telangana,INDIA
  • Product Name:Thioctic acid
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA
  • Product Name:Thioctic acid
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Reagent
  • Country/Region: Hyderabad,INDIA
  • Product Name:Thioctic acid
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Thioctic acid
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA
  • Product Name:Thioctic acid
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Uttar Pradesh,INDIA
  • Product Name:Thioctic acid
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
  • Company Type: Manufacturer
  • Country/Region: Haryana,INDIA
  • Product Name:Alpha Lipoic Acid
  • Products Intro:Purity: >98% | Package: As per requirement
  • Company Type: Manufacturer
  • Country/Region: Mumbai,INDIA
  • Product Name:Thioctic acid
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Alpha Lipoic acid/Thioctic acid IP/Ph. Eur/ USP/BP
  • Products Intro:Purity: >98% | Package: 25kgs & 50kgs
  • Company Type: Trader
  • Country/Region: AndhraPradesh,INDIA

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