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Hydrocortisone acetate

Hydrocortisone acetate

CAS:
50-03-3
MF:
C23H32O6
MW:
404.5

Properties

Melting point:
223 °C (dec.)(lit.)
Boiling point:
446.1°C (rough estimate)
alpha 
D25 +166° (c = 0.4 in dioxane); D25 +150.7° (c = 0.5 in acetone)
Density 
d420 1.289
refractive index 
1.4593 (estimate)
Flash point:
223°C
storage temp. 
0-6°C
solubility 
Practically insoluble in water, slightly soluble in anhydrous ethanol and in methylene chloride
form 
Solid
pka
12.42±0.70(Predicted)
color 
White to Off-White
Water Solubility 
Insoluble in water.
Decomposition 
223 ºC
Merck 
14,4787
BRN 
2066841
Stability:
Stable, but may be light or moisture sensitive. Incompatible with strong oxidizing agents.
LogP
2.190

Safety Information

Symbol(GHS) 

GHS08
Signal word 
Danger
Hazard statements 
H360Df-H373
Precautionary statements 
P202-P260-P280-P308+P313-P405-P501
Hazard Codes 
Xn,T
Risk Statements 
63-10-45
Safety Statements 
36/37-45-53
WGK Germany 
3
RTECS 
GM8960000
HS Code 
29372100
Toxicity
LD50 intraperitoneal in mouse: 2300mg/kg

Use

Hydrocortisone acetate is an adrenal hormone drugs, white crystalline powder, odorless, bitter taste. The melting point is 216~222 ℃, right optical. Slightly soluble in ethanol, ether, chloroform, acetone, insoluble in water. It was synthesized by In 17α-hydroxy progesterone. Hydrocortisone acetate has important physiological activities such as anti-inflammatory, anti-viral, anti-allergic, anti-shock, reducing inflammatory exudation effect, commonly used in clinical adrenal insufficiency and autoimmune diseases. Preparations are injection, tablets, ointments and eye drops. Adding a small amount of hydrocortisone acetate in some cosmetics cortisol can increase the efficacy of anti-allergy and improve the degree of whitening of the skin, but long-term using of such substances can cause the skin produce hormone-dependent disease. Our cosmetics cosmetics specifications prescribedthathormone substances can not be added.

84 India supplier list of "Hydrocortisone acetate"

  • Product Name:Hydrocortisone acetate
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Hydrocortisone acetate
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA
  • Product Name:Hydrocortisone acetate
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Gujarat,INDIA
  • Product Name:Hydrocortisone EP Impurity-C
  • Products Intro:Purity: 98% | Package: 50 MG; 100 MG; 250 MG ; 200 MG
  • Company Type: Manufacturer
  • Country/Region: Hyderabad,INDIA
  • Product Name:Hydrocortisone acetate
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:Hydrocortisone acetate
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Hydrocortisone Acetate
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Trader
  • Country/Region: NaviMumbai,INDIA
  • Product Name:Reference Standards Hydrocortisone Acctate CRS -1 Vial EPCRS-H140000
  • Products Intro:Purity: 98.10 | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Hyderabad,INDIA
  • Product Name:Hydrocortisone acetate
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Gujarat,INDIA
  • Product Name:Hydrocortisone acetate
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Gujarat,INDIA

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