Meloxicam
Meloxicam
- CAS:
- 71125-38-7
- MF:
- C14H13N3O4S2
- MW:
- 351.4
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Properties
- Melting point:
- 255 °C
- Density
- 1.613±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble
- form
- Off-white solid
- pka
- 4.08 in water; 4.24 ± 0.01 in water/ethanol (1:1); 4.63 ± 0.03 in water/ethanol (1:4)
- color
- yellow
- Water Solubility
- practically insoluble in water(0.154 mg/mL), with higher solubility observed in strong acids and bases.
- Merck
- 14,5826
- BCS Class
- 2(CLogP), 4 (LogP)
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- InChI
- InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)
- InChIKey
- ZRVUJXDFFKFLMG-UHFFFAOYSA-N
- SMILES
- S1(=O)(=O)C2=CC=CC=C2C(O)=C(C(NC2=NC=C(C)S2)=O)N1C
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H301
- Precautionary statements
- P264-P270-P301+P310-P405-P501
- Hazard Codes
- Xn,T
- Risk Statements
- 22-36/37/38-25
- Safety Statements
- 26-45-60-36/37
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- DL0702000
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29349990
- Toxicity
- LD50 orally in mice: 470 mg/kg (Trummlitz, 1980)
Use
Meloxicam (Mobic) is a selective COX-2 inhibitor amongoxicams indicated for use in RA and OA. It also has a relativelylong half-life of 15 to 20 hours and has a much lowerrate of serious GI side effects and a lower than average riskof nephropathy when compared with other conventionalNSAIDs.196 The recommended dose is 7.5 mg once dailywith a maximum of 15 mg/d. Meloxicam is metabolized inhumans mainly by CYP2C9 (with a minor contribution viaCYP3A4) to 5'-hydroxymethylmeloxicam and 5 carboxymeloxicam.In large-scale comparative trials, meloxicam was foundto be at least as effective as most conventional NSAIDs inthe treatment of rheumatic disease or postoperative pain, buthas demonstrated a more favorable GI tolerability profile.
59 India supplier list of "Meloxicam"
- Product Name:Meloxicam
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: Maharashtra,INDIA
- Product Name:Meloxicam
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Meloxicam
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Ahmedabad,INDIA
- Product Name:Meloxicam
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Meloxicam
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Meloxicam
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Meloxicam
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Uttar Pradesh,INDIA
- Product Name:Meloxicam
- Products Intro:Purity: 99% | Package: 25 Kgs
- Company Type: Trader
- Country/Region: Maharashtra,INDIA
- Product Name:Meloxicam
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Meloxicam
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA