Ofloxacin
Ofloxacin
- CAS:
- 82419-36-1
- MF:
- C18H20FN3O4
- MW:
- 361.37
Suppliers by country/region
Company Type
Properties
- Melting point:
- 270-2750C
- Boiling point:
- 571.5±50.0 °C(Predicted)
- Density
- 1.2688 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- solubility
- 1 M NaOH: soluble50mg/mL
- pka
- 5.19±0.40(Predicted)
- form
- Solid
- color
- Colorless needles from ethanol
- Water Solubility
- Soluble in acetic acid or water. Slightly soluble in methanol
- λmax
- 326nm(H2O)(lit.)
- Merck
- 14,6771
- BCS Class
- 1
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H303
- Precautionary statements
- P270-P301+P312-P403-P501c
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-42/43-68-36/37/38
- Safety Statements
- 26-36/37/39-24/25-22-37/39-60
- WGK Germany
- 3
- RTECS
- UU8815550
- HS Code
- 29349990
- Toxicity
- LD50 in male, female mice, male, female rats (mg/kg): 5450, 5290, 3590, 3750 orally; 208, 233, 273, 276 i.v.; >10000, >10000, 7070, 9000 s.c. (Ohno)
Use
Ofloxacin is a fluoroquinolone antibiotic present as a racemic mixture. Levofloxacin, S-isomer of ofloxacin, shows a broad spectrum of antibacterial activity against both gram-positive and gram-negative bacteria. The antibacterial activity of levofloxacin is 8–128 times greater than that of the corresponding R-isomer. A novel esterase of type B1 carboxylesterase/lipase family from a marine isolate Y. lipolytica CL180 was used to resolve a racemic mixture of ofloxacin ester. This esterase showed an enantioselectivity toward R, S-ofloxacin ester, and levofloxacin was produced with an enantiomeric excess of 52 % (Kim et al. 2007).
32 India supplier list of "Ofloxacin"
- Product Name:Ofloxacin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Ofloxacin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Uttar Pradesh,INDIA
- Product Name:Ofloxacin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Ofloxacin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Ofloxacin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:Ofloxacin
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Ofloxacin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: New Delhi,INDIA
- Product Name:Ofloxacin
- Products Intro:Purity: IP/BP-EP/USP | Package: 25 Kg
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Ofloxacin
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Ofloxacin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA