Phenacetin manufacturers and suppliers in india

Phenacetin

Properties

Melting point:: 133-136 °C (lit.)

Boiling point:: 132 °C / 4mmHg

Density: 1.1248 (rough estimate)

refractive index: 1.5710

Flash point:: 2℃

storage temp.: Sealed in dry,Room Temperature

solubility: Chloroform (Slightly), Methanol (Slightly)

form: powder

pka: pKa 2.2(H2O) (Uncertain);3.5(aqueous acetone) (Uncertain)

color: White

Water Solubility: 0.076 g/100 mL

Sensitive: Hygroscopic

Merck: 14,7204

BRN: 1869238

Stability:: Stable. Incompatible with strong oxidizing agents, strong acids.

InChIKey: CPJSUEIXXCENMM-UHFFFAOYSA-N

LogP: 1.580

Safety Information

Symbol(GHS): GHS07,GHS08

Signal word: Danger

Hazard statements: H302-H350

Precautionary statements: P201-P202-P264-P270-P301+P312-P308+P313

Hazard Codes: T,F

Risk Statements: 45-22-20/21/22-36-11

Safety Statements: 53-45-36/37-26-16

RIDADR: UN 3077 9 / PGIII

WGK Germany: 3

RTECS: AM4375000

TSCA: Yes

HS Code: 29251995

Toxicity: LD50 orally in rats: 1.65 g/kg (Boyd)

Use

Long term use may cause renal papillary necrosis and interstitial nephritis, and even induce renal pelvic cancer and bladder cancer. Phenacetin also makes the hemoglobin to form methemoglobin, decreasing blood oxygen carrying capacity, causing cyanosis. In addition, Phenacetin can cause hemolysis and hemolytic anemia, and is toxic to the retina. Long term use may cause also lead to dependence. Countries including America, Britain, German, and Japan have banned Phenacetin, or required packaging to note that it is not indicated for long-term usage or large doses.