AEE788
AEE788
- CAS:
- 497839-62-0
- MF:
- C27H32N6
- MW:
- 440.58
Suppliers by country/region
Company Type
Properties
- storage temp.
- -20°C
- solubility
- ≥22.05 mg/mL in DMSO; insoluble in H2O; ≥14.4 mg/mL in EtOH with ultrasonic
- form
- powder
- color
- white to beige
Safety Information
- RTECS
- UY8836200
Use
AEE788 is an inhibitor of both epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF) receptor tyrosine kinase family members. It can inhibit EGFR and VEGFR tyrosine kinases with IC50 values of 2, 6, 77, and 59 nM for EGFR, ErbB2, KDR, and FLT1, respectively. AEE788 demonstrates antiproliferative activity against a range of EGFR and ErbB2-overexpressing cell lines and can inhibit the proliferation of EGF- and VEGF-stimulated human umbilical vein endothelial cells. It also has been shown to have antitumor and anti-angiogenic activity in numerous animal models of cancer.[Cayman Chemical]
0 India supplier list of "AEE788"
- Product Name:AEE788
- Products Intro:Brand:clearsynth | Product Number:CS-T-01425
- Company Type: Trader
- Country/Region: INDIA
- Product Name:AEE788
- Products Intro:Brand:ajchemicals | Product Number:JDH-26161 | Purity:98+%
- Company Type: Trader
- Country/Region: INDIA
- Product Name:AEE788
- Products Intro:Purity: 98% HPLC | Package: 5MG;10MG;50MG;100MG,1G,5G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:AEE-788
- Products Intro:Purity: >98% | Package: 10mg | CustNote: BOC Sciences also provides custom synthesis services for AEE-788.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:6-(4-((4-ethyl-1-piperazinyl)methyl)phenyl)-n-((1r)-1-phenylethyl)-7h-pyrrolo(2,3-d)pyrimidin-4-amine
- Products Intro:Purity: 0.99 | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:AEE788
- Products Intro:Purity: 98% | Package: 1KG;3USD
- Company Type: Trader
- Country/Region: CHINA
$3.00/ 1KG
- Product Name:AEE788；NVP-AEE 788
- Products Intro:Purity: 100.00% | Package: 10 mg；100 mg；2 mg；200 mg；5 mg；50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:AEE788
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:AEE788
- Products Intro:Purity: 98% | Package: 1g,10g,25g,100g,500g,1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:AEE788 NVP-AEE788
- Products Intro:Purity: 99% | Package: 5KG;1KG
- Company Type: Trader
- Country/Region: CHINA