Amtolmetin guacil
Amtolmetin guacil
- CAS:
- 87344-06-7
- MF:
- C24H24N2O5
- MW:
- 420.46
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Company Type
Properties
- Melting point:
- 117-120°
- Boiling point:
- 663.3±55.0 °C(Predicted)
- Density
- 1.19±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 13.90±0.46(Predicted)
- color
- Pale Brown to Light Brown
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P330-P501
- Toxicity
- LD50 in male mice, rats (mg/kg): 1370, 1100 i.p.; >1500, 1450 orally (Baglioni)
Use
Amtolmetin guacil is an orally active non-steroidal antiinflammatory drug (NSAID) introduced for the treatment of osteoarthritis, rheumatoid arthritis and post-operative pain. Amtolmetin guacil is reported to elicit a more rapid and improved analgesic action than other agents such as paracetamol. In models of adjuvant arthritis and rheumatic diseases, amtolmetin guacil is more efficacious than existing drugs such as naproxen, indomethacin and piroxicam. As a non-acidic prodrug of tolmetin, it has similar in vivo activity to the parent but with minor ulcerogenic action, lower acute toxicity, and excellent biological and gastric tolerability.
6 India supplier list of "Amtolmetin guacil"
- Product Name:Amtolmetin Guacil
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Hyderabad,INDIA
- Product Name:Amtolmetin Guacil
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Amtolmetin guacil 95%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.130279
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Amtolmetin Guacil
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Amtolmetin Guacil
- Company Type: Reagent
- Country/Region: Ahmedabad,INDIA
- Product Name:Amtolmetinguacil
- Products Intro:Brand:ajchemicals | Product Number:JDH-55574 | Purity:95%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:AmtolmetinGuacil
- Products Intro:Brand:pharmaffiliates | Product Number:PA2867000
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:Amtolmetin guacil
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:Amtolmetinguacil
- Products Intro:Brand:clearsynth | Product Number:CS-O-00833
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Amtolmetin
- Products Intro:Brand:synzeal | Product Number:103931725
- Company Type: Trader
- Country/Region: Gujarat,INDIA