Amtolmetin guacil
- CAS No.
- 87344-06-7
- Chemical Name:
- Amtolmetin guacil
- Synonyms
- med15;Eufans;ArtroMed;Amtolmetin;AMTOLMETIN GUACIL;AMtolMetin Guacyl;AMTOLMETIO GUACIL;AMtolMethin Guacil;2-methoxyphenyl1-methyl-5-p-methylbenzoylpyrrole-2-acetoamidoacetate;n-((1-methyl-5-(4-methylbenzoyl)-1h-pyrrol-2-yl)acetyl)-glycin2-methoxyphe
- CBNumber:
- CB0129750
- Molecular Formula:
- C24H24N2O5
- Molecular Weight:
- 420.46
- MOL File:
- 87344-06-7.mol
- Modify Date:
- 2024/3/19 15:37:51
Melting point | 117-120° |
---|---|
Boiling point | 663.3±55.0 °C(Predicted) |
Density | 1.19±0.1 g/cm3(Predicted) |
storage temp. | Sealed in dry,Room Temperature |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | 13.90±0.46(Predicted) |
color | Pale Brown to Light Brown |
CAS DataBase Reference | 87344-06-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P264-P270-P301+P312-P330-P501 |
Toxicity | LD50 in male mice, rats (mg/kg): 1370, 1100 i.p.; >1500, 1450 orally (Baglioni) |
Amtolmetin guacil Chemical Properties,Uses,Production
Description
Amtolmetin guacil is an orally active non-steroidal antiinflammatory drug (NSAID) introduced for the treatment of osteoarthritis, rheumatoid arthritis and post-operative pain. Amtolmetin guacil is reported to elicit a more rapid and improved analgesic action than other agents such as paracetamol. In models of adjuvant arthritis and rheumatic diseases, amtolmetin guacil is more efficacious than existing drugs such as naproxen, indomethacin and piroxicam. As a non-acidic prodrug of tolmetin, it has similar in vivo activity to the parent but with minor ulcerogenic action, lower acute toxicity, and excellent biological and gastric tolerability.
Uses
Analgesic; anti-inflammatory used in the treatment of rheumatoid arthritis,
Amtolmetin guacil Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 83)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Hetero Drugs Limited | +91-4023704923 +91-4023704923 | Telangana, India | 296 | 58 | Inquiry |
Sai Life Sciences Ltd | +91-4066777555 +91-8008555365 | Hyderabad, India | 24 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
EMCURE PHARMACEUTICALS LIMITED | +1 (866)- 901- 3784 | New Delhi, India | 31 | 58 | Inquiry |
Advances Pharamlab Limited | 08048250469Ext 719 | Ahmedabad, India | 1 | 58 | Inquiry |
Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
87344-06-7(Amtolmetin guacil)Related Search:
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2-(2-Methoxyphenyl)-2-(N-{1-Methyl-5-[(4-Methylphenyl)carbonyl]-1H-pyrrol-2-yl}acetaMido)acetate
ArtroMed
Eufans
AMtolMethin Guacil
AMtolMetin Guacyl
N-[2-[1-Methyl-5-(4-Methylbenzoyl)-1H-pyrrol-2-yl]acetyl]glycine 2-Methoxyphenyl Ester
2-Methoxyphenyl 2-(2-(1-Methyl-5-(4-Methylbenzoyl)-1H-pyrrol-2-yl)acetaMido)acetate
2-methoxyphenyl1-methyl-5-p-methylbenzoylpyrrole-2-acetoamidoacetate
med15
n-((1-methyl-5-(4-methylbenzoyl)-1h-pyrrol-2-yl)acetyl)-glycin2-methoxyphe
AMTOLMETIN GUACIL
Amtolmetin
AMTOLMETIO GUACIL
2-Methoxyphenyl 2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetylamino)acetate
N-[[5-(4-Methylbenzoyl)-1-methyl-1H-pyrrol-2-yl]acetyl]glycine 2-methoxyphenyl ester
Amtolmetin guacilQ: What is
Amtolmetin guacil Q: What is the CAS Number of
Amtolmetin guacil Q: What is the storage condition of
Amtolmetin guacil Q: What are the applications of
Amtolmetin guacil
Glycine, N-[2-[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetyl]-, 2-methoxyphenyl ester
87344-06-7
C24H24N2O5
Aromatics
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals