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Atorvastatin

Atorvastatin

CAS:
134523-00-5
MF:
C33H35FN2O5
MW:
558.65

Properties

Melting point:
176-178°C
Boiling point:
722.2±60.0 °C(Predicted)
Density 
1.23±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: 100 mg/mL (179.01 mM)
pka
pKa 4.46(H2O t=30 Iuncontrolled) (Uncertain)
form 
Solid
color 
White to light yellow

Safety Information

Symbol(GHS) 

GHS03,GHS07
Signal word 
Warning
Hazard statements 
H272-H315-H319-H335
Precautionary statements 
P221-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P370+P378r-P370+P380+P375-P380-P501c
Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36
HS Code 
35040000

Use

Atorvastatin, [R-(R*,R*)]-2-(4-fluorophenyl)-b,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-lH-pyrrole-1-heptanoic acid(Lipitor), also possesses the heptanoic acid side chain,which is critical for inhibition of HMG-CoA reductase.Although the side chain is less lipophilic than the lactoneform, the high amount of lipophilic substitution causes this agent to have a slightly higher level of CNS penetration thanpravastatin, resulting in a slight increase in CNS side effects.Even so, its CNS profile is much lower than that of lovastatin.Atorvastatin is marketed as a combination therapywith amlodipine under the trade name Norvasc for managementof high cholesterol and high blood pressure.

35 India supplier list of "Atorvastatin"

  • Product Name:Atorvastatin
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Gujarat,INDIA
  • Product Name:ATORVASTATIN CALCIUM
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Gujarat,INDIA
  • Product Name:Atorvastatin Acid
  • Products Intro:Purity: 98% | Package: 50 MG; 100 MG; 250 MG ; 600 MG
  • Company Type: Manufacturer
  • Country/Region: Hyderabad,INDIA
  • Product Name:Atorvastatin
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA
  • Product Name:Atorvastatin
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA
  • Product Name:Atorvastatin
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Atorvastatin
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Atorvastatin
  • Products Intro:Purity: 98% | Package: 25mg; 50mg; 100mg; Customised
  • Company Type: Trader
  • Country/Region: Punjab,INDIA
  • Product Name:Atorvastatin Acid
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Gujarat,INDIA
  • Product Name:Thiosalicylic acid
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA

Atorvastatin Related Search:

Diphenyl etherPolyvinylpyrrolidonePhenyl salicylateSimvastatinPyrrolidineN-Vinyl-2-pyrrolidonePROPANEN-Methyl-2-pyrrolidoneATORVASTATIN SODIUMPhenylacetic acidAtorvastatin tert-Butyl EsterO-HYDROXY ATORVASTATIN LACTONE(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetateAcrivastineHeptanoic acidAtorvastatinP-HYDROXY ATORVASTATIN LACTONE
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