Bivalirudin manufacturers and suppliers in india

Bivalirudin

Properties

Density: 1.52±0.1 g/cm3(Predicted)

storage temp.: -20°C

solubility: ≥54.5 mg/mL in DMSO with gentle warming; ≥10.18 mg/mL in EtOH with gentle warming and ultrasonic; ≥43.5 mg/mL in H2O with gentle warming

form: powder

color: white to off-white

Sequence: D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH

InChIKey: OIRCOABEOLEUMC-GEJPAHFPSA-N

Safety Information

Precautionary statements: P271-P261-P280

WGK Germany: 3

HS Code: 3504009000

Use

Bivalirubin is a synthetic 20 amino acid peptide rationally modeled on hirudin (residues 53- 64), the most potent and specific naturally-occuring known inhibitor of thrombin, the enzyme that plays a key role in hemostasis and blood clot formation. This peptide is a direct thrombin inhibitor that maintains the unique bivalent binding properties of hirudin to the catalytic site and to the fibrin-recognition exosite of the enzyme, so acting directly on thrombin with high affinity and specificity.