CHIR-090
CHIR-090
- CAS:
- 728865-23-4
- MF:
- C24H27N3O5
- MW:
- 437.49
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Properties
- Density
- 1.33±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- ≥21.85 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
- form
- solid
- pka
- 9.11±0.40(Predicted)
- color
- White to off-white
Safety Information
- Symbol(GHS)
GHS05,GHS08
- Signal word
- Danger
- Hazard statements
- H315-H318-H334-H317-H341-H361-H370-H413
Use
CHIR-090 is the first reported compound that in fact kills both E. coli and Pseudomonas aeruginosa in bacterial disk diffusion assays (Liang et al. 2011). Nonetheless, CHIR-090 was about 600-fold less effective against LpxC orthologs from the Rhizobiaceae family than against E. coli LpxC. In this way, studies have shown that the removal of morpholine ring, based on a chemical scaffold of reduced radius, was able to increase affinity by 20-fold for LpxC enzymes from the Rhizobiaceae family of bacteria and enhance the antibiotic activity against E. coli and P. aeruginosa by 2–4 fold over CHIR-090.
0 India supplier list of "CHIR-090"
- Product Name:CHIR-090
- Products Intro:Brand:sigma aldrich | Product Number:SML3092 | Purity:≥98%(HPLC)
- Company Type: Trader
- Country/Region: INDIA
- Product Name:CHIR-090
- Products Intro:Brand:ajchemicals | Product Number:JDH-27607 | Purity:98+%
- Company Type: Trader
- Country/Region: INDIA
- Product Name:CHIR-090
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:CHIR-090
- Products Intro:Purity: 98% | Package: 300mg | CustNote: BOC Sciences also provides custom synthesis services for CHIR-090.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[2-[4-(morpholin-4-ylmethyl)phenyl]ethynyl]benzamide
- Products Intro:Purity: Min98% HPLC | Package: 1KG;1USD
- Company Type: Trader
- Country/Region: CHINA
$1.00/ 1KG
- Product Name:CHIR-090
- Products Intro:Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Hot selling
- Company Type: Trader
- Country/Region: CHINA
- Product Name:CHIR-090
- Products Intro:Purity: 99% | Package: 5KG;1KG | CustNote: CHIR-090
- Company Type: Trader
- Country/Region: CHINA
- Product Name:CHIR-090；CHIR090;CHIR 090
- Products Intro:Package: 1 mL * 10mM (in DMSO)；10 mg；2 mg；25 mg；5 mg；50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Reagent
- Country/Region: UNITED STATES
- Product Name:CHIR-090
- Products Intro:Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Hot selling
- Company Type: Trader
- Country/Region: CHINA
- Product Name:CHIR-090
- Products Intro:Purity: 99 | Package: 5KG;1KG,25kg
- Company Type: Trader
- Country/Region: CHINA