Chlorobutanol manufacturers and suppliers in india

Chlorobutanol

Properties

Melting point:: ~78 °C

Boiling point:: 173 °C

Density: 1.3170 (estimate)

Flash point:: >110°C

storage temp.: Sealed in dry,Room Temperature

solubility: Slightly soluble in water, very soluble in ethanol (96 per cent), soluble in glycerol (85 per cent).

form: Solid

pka: 12.87±0.29(Predicted)

color: Hydrated crystals

Odor: camphor odor

Water Solubility: 8g/L(20 ºC)

Stability:: Stable. Generates toxic fumes on combustion.

LogP: 2.030

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H315-H319-H335

Precautionary statements: P261-P280-P301+P312-P302+P352-P305+P351+P338

Hazard Codes: Xn

Risk Statements: 22-36/37/38

Safety Statements: 26-36/37/39

WGK Germany: 3

Toxicity: MLD orally in dogs, rabbits (mg/kg): 238, 213 (Impens)

Use

Chlorobutanol is volatile and readily sublimes. In aqueous solution, degradation to carbon monoxide, acetone and chloride ion is catalyzed by hydroxide ions. Stability is good at pH 3 but becomes progressively worse with increasing pH. The half-life at pH 7.5 for a chlorobutanol solution stored at 258℃ was determined to be approximately 3 months. In a 0.5% w/v aqueous chlorobutanol solution at room temperature, chlorobutanol is almost saturated and may crystallize out of solution if the temperature is reduced. Losses of chlorobutanol also occur owing to its volatility, with appreciable amounts being lost during autoclaving; at pH 5 about 30% of chlorobutanol is lost. Porous containers result in losses from solutions, and polyethylene containers result in rapid loss. Losses of chlorobutanol during autoclaving in polyethylene containers may be reduced by pre-autoclaving the containers in a solution of chlorobutanol; the containers should then be used immediately. There is also appreciable loss of chlorobutanol through stoppers in parenteral vials. The bulk material should be stored in an airtight container at a temperature of 8–158℃.