COLLISMYCIN A manufacturers and suppliers in india

COLLISMYCIN A

CAS:: 158792-24-6

MF:: C13H13N3O2S

MW:: 275.33

Suppliers by country/region

Company Type

Properties

Melting point:: 173-174 °C

Boiling point:: 450.7±45.0 °C(Predicted)

Density: 1.27±0.1 g/cm3(Predicted)

storage temp.: 2-8°C

solubility: DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble

form: A solid

pka: 9.75±0.50(Predicted)

Safety Information

Use

Collismycin is a rare and unusual antibiotic belonging to the caerulomycin class, containing a core 2,2’-bispyridyl with an oxime substituent, produced by a strain of Streptomyces and discovered by researchers from Kirin, Japan in 1994. Collismycin was discovered as a potent inhibitor of glucocorticoid receptor binding. Collismycin has weak to moderate activity against bacteria, fungi and tumor cell lines. More recently, collismycin has been found to be a potent and selective neuroprotective agent against oxidative stress. Other recent publications have focused on the biosynthesis of collismycin as a route to the production of related analogues.