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Cyclophosphamide

Cyclophosphamide

CAS:
50-18-0
MF:
C7H15Cl2N2O2P
MW:
261.09

Properties

Melting point:
41-45°C
Boiling point:
336.1±52.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
≥11.85 mg/mL in H2O with gentle warming and ultrasonic; ≥13.05 mg/mL in DMSO; ≥50.8 mg/mL in EtOH
form 
solid
pka
2.84±0.20(Predicted)
color 
White to off-white
Water Solubility 
Soluble. 1-5 g/100 mL at 23 ºC
BCS Class
1,3
Stability:
Stable, but light sensitive. Incompatible with oxidizing agents.

Safety Information

Symbol(GHS) 

GHS08,GHS06
Signal word 
Danger
Hazard statements 
H301-H360-H340-H350
Precautionary statements 
P264-P270-P301+P310-P321-P330-P405-P501
Safety Statements 
22-24/25
RIDADR 
UN 1851
HazardClass 
6.1(b)
PackingGroup 
III
Toxicity
LD50 oral in rat: 100mg/kg

Use

Cyclophosphamide is a component of CMF (cyclophosphamide, methotrexate, 5-fluorouracil) and other drug combinations used in the treatment of breast cancer. Cyclophosphamide in combination may produce complete remissions in some patients with ovarian cancer and oat cell (small cell) lung cancer. Other tumors in which beneficial results have been reported include non–oat cell lung cancers, various sarcomas, neuroblastoma, and carcinomas of the testes, cervix, and bladder. Cyclophosphamide also can be employed as an alternative to azathioprine in suppressing immunological rejection of transplant organs.

26 India supplier list of "Cyclophosphamide"

  • Product Name:Cyclophosphamide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Mumbai,INDIA
  • Product Name:Cyclophosphamide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Telangana,INDIA
  • Product Name:Cyclophosphamide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Pune,INDIA
  • Product Name:Cyclophosphamide
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Karnataka,INDIA
  • Product Name:Cyclophosphamide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Cyclophosphamide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:Cyclophosphamide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Cyclophosphamide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Cyclophosphamide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Hyderabad,INDIA
  • Product Name:Cyclophosphamide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
  • Company Type: Manufacturer
  • Country/Region: Telangana,INDIA

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