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D-Thyroxine

D-Thyroxine

CAS:
51-49-0
MF:
C15H11I4NO4
MW:
776.87

Properties

Melting point:
~235 °C (dec.)
alpha 
21546 +2.97° (0.74 g in 6 g of 0.5N NaOH and 14 g of alcohol)
Boiling point:
576.3±50.0 °C(Predicted)
Density 
2.4440 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
Acidic Alcohol (Slightly), Aqueous Acid (Slightly, Sonicated), Aqueous Base (Slightly)
form 
Solid
pka
2.12±0.30(Predicted)
color 
Off-White to Beige
Stability:
Hygroscopic

Safety Information

Symbol(GHS) 

GHS07
Signal word 
Warning
Hazard statements 
H312-H302-H332
Precautionary statements 
P280-P302+P352-P312-P322-P363-P501-P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501
Hazard Codes 
Xn
Risk Statements 
20/21/22-40
Safety Statements 
36/37-36-22
WGK Germany 
3
8-10

Use

Recrystallise D-thyroxine from H2O (needles) or from an ammonical solution by dilution with H2O, MeOH or Me2CO. It has also been purified by dissolving ~6.5 g in a mixture of MeOH (200mL) and 2N HCl (20mL), adding charcoal, filtering then adding NaOAc solution to pH 6. On standing the thyroxine separates, it is filtered off, washed with MeOH then Me2CO and dried in vacuo. N-Formyl-D-thyroxine has m 210o and [] 21 -26.9o (c 5, EtOH). (±)-Thyroxine has m 256o and is purified in the same way. [Nahm & Siedel Chem Ber 96 1 1963, Salter Biochem J 24 471 1930, Beilstein 14 I 671, 14 II 384, 14 III 1566, 14 IV 2374.]

1 India supplier list of "D-Thyroxine "

  • Product Name:D-Thyroxine 96%
  • Products Intro:Brand:Glrinnovations | OriginalID:GLR19.165013
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:Levothyroxine D-Isomer
  • Products Intro:Brand:synzeal | Product Number:122534214
  • Company Type: Trader
  • Country/Region: Gujarat,INDIA
  • Product Name:D-Thyroxine
  • Products Intro:Brand:clearsynth | Product Number:CS-T-62056
  • Company Type: Trader
  • Country/Region: Hyderabad,INDIA
  • Product Name:LevothyroxineD-Isomer
  • Products Intro:Brand:pharmaffiliates | Product Number:PA1215710
  • Company Type: Trader
  • Country/Region: Haryana,INDIA
  • Product Name:(R)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoicacid
  • Products Intro:Brand:ajchemicals | Product Number:JDH-2482 | Purity:95+%
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:d-thyroxine
  • Products Intro:Purity: 99% | Package: 1kg
  • Company Type: Trader
  • Country/Region: CHINA

    $1.00/ 1KG

  • Product Name:D-Thyroxine
  • Products Intro:Purity: 99% | Package: 1KG;1USD
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:D-Thyroxine
  • Company Type: Reagent
  • Country/Region: CHINA
  • Main Products: Gamma-butyrolactone
  • Product Name:D-Thyroxine
  • Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Dextrothyroxine
  • Company Type: Reagent
  • Country/Region: UNITED STATES
  • Main Products: Active Pharmaceutical Ingredient (API),Insect Pheromone,Boronic Compounds,Material & Chemicals,Lipid Compounds

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