Davercin
Davercin
- CAS:
- 55224-05-0
- MF:
- C38H65NO14
- MW:
- 759.93
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Properties
- Melting point:
- >135°C (dec.)
- Boiling point:
- 859.8±65.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
- pka
- 13.49±0.70(Predicted)
- form
- Solid
- color
- White
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P330-P501
- Toxicity
- LD50 oral in rat: 5800mg/kg
Use
Davercin (erythromycin A cyclic 11,12-carbonate) is a first generation semi-synthetic erythromycin. Davercin is prepared by coupling the 11- and 12-OH groups to form a cyclic carbonate. This simple modification improves the stability and hydrophobicity of the macrocyclic structure. Davercin shows comparable or better in vitro potency, low host toxicity and improved pharmacokinetics compared with erythromycin.
1 India supplier list of "Davercin"
- Product Name:Davercin
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:ErythromycinCyclocarbonate
- Products Intro:Brand:pharmaffiliates | Product Number:PA050151001
- Company Type: Trader
- Country/Region: Haryana,INDIA