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Davercin

Davercin Structure
CAS No.
55224-05-0
Chemical Name:
Davercin
Synonyms
Erythromycin Cyclocarbonate;erythromycin A cyclic 11,12-carbonate;CWE;DAVERCIN;Dravercin;Davercin USP/EP/BP;Erythromycin cycloester;Davercin, 10 mM in DMSO;Eritromicina A carbonato;Erythromycin Impurity 10
CBNumber:
CB2966540
Molecular Formula:
C38H65NO14
Molecular Weight:
759.93
MOL File:
55224-05-0.mol
MSDS File:
SDS
Modify Date:
2026/8/5 9:01:00
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Davercin Properties

Melting point >135°C (dec.)
Boiling point 859.8±65.0 °C(Predicted)
Density 1.22±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka 13.49±0.70(Predicted)
form Solid
color White

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Toxicity LD50 oral in rat: 5800mg/kg

Davercin price

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Davercin Chemical Properties,Uses,Production

Description

Davercin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It has broad-spectrum activity against various Gram-positive and Gram-negative bacteria (MICs = 0.02-50 μg/ml). Davercin is non-toxic to mice and rats (LD50s = 4.05 and 5.9 g/kg, respectively). Formulations containing davercin have been used to treat a variety of urogenital bacterial infections.

Uses

Davercin (erythromycin A cyclic 11,12-carbonate) is a first generation semi-synthetic erythromycin. Davercin is prepared by coupling the 11- and 12-OH groups to form a cyclic carbonate. This simple modification improves the stability and hydrophobicity of the macrocyclic structure. Davercin shows comparable or better in vitro potency, low host toxicity and improved pharmacokinetics compared with erythromycin.

Davercin Preparation Products And Raw materials

Raw materials

Preparation Products

Davercin Suppliers

Global( 147)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6053 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6094 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6666 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6727 58 Inquiry
Anuh Pharma Ltd +91 22 6622 7575 Beijing, India 33 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32997 60 Inquiry
career henan chemical co +86-0371-86658258 China 29763 58 Inquiry
CONIER CHEM AND PHARMA LIMITED China 49899 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-29-87569262 +86-15003564040 China 3969 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 United States 32431 58 Inquiry
Supplier Advantage
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Pharma Affiliates 58
Anuh Pharma Ltd 58
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
CONIER CHEM AND PHARMA LIMITED 58
Shaanxi Dideu Medichem Co. Ltd 58
TargetMol Chemicals Inc. 58

Davercin Spectrum

Davercin(55224-05-0)1HNMR

55224-05-0(Davercin)Related Search:

Chlorophosphonazo III Calcium carbonate CYCLANDELATE Erythromycin Impurity 9 Roxithromycin
Sodium carbonate Dimethyl carbonate Ethylene carbonate Lithium carbonate 3-Dimethylaminopropylamine
Erythromycin Cyclopentolate (S)-(-)-Propylene Carbonate (R)-(+)-Propylene carbonate Dibutyl carbonate
4-Hydroxymethyl-1,3-dioxolan-2-one 4-Ethyl-1,3-dioxolan-2-one (R)-(+)-4-(Methoxymethyl)-1,3-dioxolan-2-one
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DAVERCIN CWE (1R,2R,5R,6S,7S,9R,11R,13R,14R)-8-[(2S,3R,4S,6R)-4-Dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-9-hydroxy-6-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-1,5,7,9,11,13-hexamethyl-3,15,17-trioxabicyclo[12.3.0]heptadecane-4,12,16-trione Carbonato ciclico de eritromicina a Carbonato ciclico de eritromicina A [spanish] Cykliczny weglan erytromycyny a Cykliczny weglan erytromycyny A [polish] Dravercin Eritromicina A carbonato Eritromicina A carbonato [spanish] ErythroMycin A 11,12-carbonate, ErythroMycin A cyclic 11,12-carbonate, ErythroMycin cyclic carbonate Cyclic ester of erythroMycin cyclic 11,12-carbonate erythromycin Erythromycin Impurity 10 Erythromycin Cyclocarbonate, >98% Erythromycin, cyclic 11,12-carbonate Erythromycin Impurity 20（Erythromycin Cyclocarbonate） Davercin USP/EP/BP Erythromycin Cyclic11,12-Carbonate(Davercin) Erythromycin Impurity 50 (3aR,4R,7R,8S,9S,10R,11R,13R,15R,15aR)-10-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-ethyl-11-hydroxy-8-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3a,7,9,11,13,15-hexamethyloctahy Davercin (Erythromycin cyclocarbonate) erythromycin A cyclic 11,12-carbonate Erythromycin cycloester Erythromycin cyclic carbonate Erythromycin Impurity 10(Davercin) Davercin, 10 mM in DMSO Erythromycin cyclocarbonate (Davercin) Cyclic ester erythromycin Erythromycin Cyclocarbonate 55224-05-0 C38H65NO14 Inhibitors 55224-05-0