DEOXYNIVALENOL
DEOXYNIVALENOL
- CAS:
- 51481-10-8
- MF:
- C15H20O6
- MW:
- 296.32
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Properties
- Melting point:
- 151-153 C
- alpha
- D25+6.35° (c = 0.07 in ethanol)
- Boiling point:
- 357.92°C (rough estimate)
- Density
- 1.48
- refractive index
- 1.4359 (estimate)
- Flash point:
- -3 °C
- storage temp.
- -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
- pka
- 11.91±0.70(Predicted)
- form
- solution (ethanol: 2-propanol 95:5)
- color
- White to off-white
- Merck
- 13,10092
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- InChI
- InChI=1/C15H20O6/c1-7-3-9-14(5-16,11(19)10(7)18)13(2)4-8(17)12(21-9)15(13)6-20-15/h3,8-9,11-12,16-17,19H,4-6H2,1-2H3/t8-,9-,11-,12-,13-,14-,15+/s3
- InChIKey
- LINOMUASTDIRTM-QUKTVYMZNA-N
- SMILES
- [C@@]12(CO1)[C@@]1([H])[C@H](O)C[C@]2(C)[C@@]2(CO)[C@H](O)C(C(C)=C[C@@]2([H])O1)=O |&1:0,3,5,8,10,13,19,r|
- LogP
- -1.250 (est)
Safety Information
- Symbol(GHS)
GHS02,GHS07,GHS08
- Signal word
- Danger
- Hazard statements
- H225-H319-H336-H371
- Precautionary statements
- P210-P305+P351+P338-P308+P311
- Hazard Codes
- T,Xn,F,Xi
- Risk Statements
- 25-68/20/21/22-67-66-36-20/21/22-11-36/37/38
- Safety Statements
- 36/37/39-45-36-26-16-36/37-37/39
- RIDADR
- UN 2811 6.1/PG 2
- WGK Germany
- 3
- RTECS
- YD0167000
- HazardClass
- 6.1(a)
- PackingGroup
- I
- HS Code
- 29329990
- Toxicity
- LD50 i.p. in male, female mice (mg/kg): 70.0, 76.7 (Yoshizawa, Morooka)
Use
Deoxynivalenol is a tricothecene mycotoxin and potent protein synthesis inhibitor. Deoxynivalenol exhibits cytotoxic activity in vivo via the ribotoxic stress response. Deoxynivalenol induces p38-mediated gene expression and apoptosis in leukocytes; activity results in systemic expression of interleukin-6 (IL-6) and other proinflammatory cytokines. Also induces migration of NF-κB into the nucleus.
1 India supplier list of "DEOXYNIVALENOL"
- Product Name:Deoxynivalenol
- Products Intro:Brand:sigma aldrich | Product Number:32943 | Purity:referencematerial
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Deoxynivalenol
- Products Intro:Brand:pharmaffiliates | Product Number:PA3156000
- Company Type: Trader
- Country/Region: INDIA
- Product Name:DEOXYNIVALENOL
- Company Type: Reagent
- Country/Region: INDIA
$1.00/ 1KG
- Product Name:DEOXYNIVALENOL
- Products Intro:Purity: 99.0% | Package: 1KG;1USD
- Company Type: Trader
- Country/Region: CHINA