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Diosmin

Diosmin

CAS:
520-27-4
MF:
C28H32O15
MW:
608.54

Properties

Melting point:
277-278°C
Boiling point:
926.8±65.0 °C(Predicted)
Density 
1.68±0.1 g/cm3(Predicted)
vapor pressure 
0Pa at 20℃
storage temp. 
Sealed in dry,2-8°C
solubility 
Practically insoluble in water, soluble in dimethyl sulfoxide, practically insoluble in alcohol. It dissolves in dilute solutions of alkali hydroxides.
form 
Solid
pka
6.10±0.40(Predicted)
color 
Pale Beige to Brown
Water Solubility 
Soluble in DMSO (50 mg/ml), water (122 mg/ml at 25°C), and ethanol (<1 mg/ml at 25°C).
λmax
345nm(EtOH)(lit.)
Merck 
14,3297
InChIKey
GZSOSUNBTXMUFQ-YFAPSIMESA-N
LogP
0.14 at 20℃

Safety Information

Symbol(GHS) 
GHS hazard pictograms
GHS07
Signal word 
Warning
Hazard statements 
H302-H315-H319-H412
Precautionary statements 
P501-P273-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330
Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-36/37-24/25
WGK Germany 
3
HS Code 
29381000

Use

Diosmin is an agonist of the aryl hydrocarbon receptor (AhR) and exhibits anti-proliferative and anti-inflammatory. It is used in the treatment of venous disease, i.e., chronic venous insufficiency (CVI) and hemorrhoidal disease (HD). Diosmin also reduces capillary hyperpermeability and expression of endothelial adhesion molecules (ICAM1, VCAM1). It effectively inhibits the P-glycoprotein (Pgp)-mediated efflux in cells.

23 India supplier list of "Diosmin"

Bajaj Healthcare Ltd
  • Product Name:Diosmin
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
Sindhu Organics Pvt Ltd
  • Product Name:Diosmin
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
Molsyns Research
  • Product Name:Diosmin Reference Standard
  • Products Intro:Purity: 98% | Package: 25mg; 50mg;100mg and 1 g
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
AKASH PHARMA EXPORTS
  • Product Name:Diosmin
  • Products Intro:Purity: 99% | Package: 1kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Kerela,INDIA
Penam Laboratories Ltd
  • Product Name:Diosmin
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: New Delhi,INDIA
Sigma-Aldrich Chemicals Private Limited
  • Product Name:Diosmin
  • Products Intro:Brand:sigma aldrich | Product Number:61386 | Purity:analyticalstandard
  • Company Type: Trader
  • Country/Region: Bangalore,INDIA
  • Product Name:Diosmin >98% (HPLC), powder
  • Products Intro:Brand:Glrinnovations | OriginalID:GLR19.070863
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:Diosmin
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
Symbolic Pharma
  • Product Name:Diosmin
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
SynZeal Research Pvt Ltd
  • Product Name:Diosmin
  • Products Intro:Brand:synzeal | Product Number:192987627
  • Company Type: Trader
  • Country/Region: Gujarat,INDIA

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