DMOG
DMOG
- CAS:
- 89464-63-1
- MF:
- C6H9NO5
- MW:
- 175.14
Suppliers by country/region
Company Type
Properties
- Melting point:
- 46-48°C
- Boiling point:
- 179-182 °C(Press: 12 Torr)
- Density
- 1.246±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- H2O: >30mg/mL
- pka
- 10.55±0.46(Predicted)
- form
- Solid
- color
- white to off-white
- Water Solubility
- Soluble in water at 30mg/ml.
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions are not stable. Solutions must be made fresh and used within 1 working day.
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P301+P312+P330
- Hazard Codes
- Xi,Xn
- Risk Statements
- 22
- WGK Germany
- 3
- HS Code
- 2924.19.8000
- HazardClass
- IRRITANT
Use
DMOG is a cell permeable prolyl-4-hydroxylase inhibitor which upregulates HIF activity. HIF activation stimulates angiogenesis in several different models (1nM). DMOG also inhibits FIH (factor inhibiting HIF), an asparaginyl hydroxylase, which enhances the HIF response. It is active in vivo and attenuates myocardial injury in a rabbit ischemia reperfusion model (20mg/Kg).
1 India supplier list of "DMOG"
- Product Name:HIF-HydroxylaseInhibitor,DMOG-CAS89464-63-1-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:400091 | Purity:TheHIF-HydroxylaseInhibitor,DMOG,alsoreferencedunderCAS89464-63-1,controlsthebio
- Company Type: Trader
- Country/Region: INDIA