DOXEPIN
DOXEPIN
- CAS:
- 1668-19-5
- MF:
- C19H21NO
- MW:
- 279.38
Suppliers by country/region
Company Type
Properties
- Melting point:
- 187-189°C
- Boiling point:
- bp0.03 154-157°; bp0.2 260-270°
- Density
- 1.0594 (rough estimate)
- refractive index
- 1.5000 (estimate)
- storage temp.
- Sealed in dry,2-8°C
- pka
- 9.40±0.28(Predicted)
- Water Solubility
- 31.57mg/L(25 ºC)
Safety Information
- Hazard Codes
- T
- Risk Statements
- 25
- Safety Statements
- 36/37/39-45
- Toxicity
- LD50 in mice, rats (mg/kg): 26, 16 i.v.; 79, 182 i.p.; 135, 147 orally (Ribbentrop, Schaumann)
Use
Doxepin, a tricyclic antidepressant was introduced in 1964 for the management of endogenous depression. Much of the adverse effects are caused by its antimuscarinic actions. These include dry mouth, cardiac arrhythmias, central nervous system disturbances, blood disorders and risk of suicide. The risk of suicide and dangers related to overdosage led the Norwegian Medicines Control Authority to put the higher strength formulation under prescribing restriction in 1992. The risk of death following overdosage is apparently higher for products containing tricyclic compounds as compared with nontricyclic products.
2 India supplier list of "DOXEPIN"
- Product Name:Doxepin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenz[b,e]oxepin
- Products Intro:Brand:pharmaffiliates | Product Number:PAI31038001
- Company Type: Trader
- Country/Region: INDIA
- Product Name:DOXEPIN
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Doxepin
- Products Intro:Brand:clearsynth | Product Number:CS-O-01335
- Company Type: Trader
- Country/Region: INDIA
- Product Name:DOXEPIN
- Products Intro:Purity: 99% | Package: 1KG;7USD
- Company Type: Trader
- Country/Region: CHINA
$7.00/ 1KG
- Product Name:Doxepin
- Products Intro:Purity: NLT 98% | CustNote: MC530356
- Company Type: Manufacturer
- Country/Region: CHINA
- Product Name:doxepin
- Products Intro:Purity: 98% | Package: $119.9/100mg;$199.9/250mg;$499.9/1g;$1400.9/5mg;$2000.9/25mg;Bulk package | CustNote: 98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:Doxepin
- Products Intro:Brand：glenthamls | Product Number：GP9511
- Company Type: Trader
- Country/Region: UNITED KINGDOM
- Product Name:3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine
- Products Intro:Brand：a2bchem | Product Number：AA89177
- Company Type: Trader
- Country/Region: UNITED STATES