Gallic acid manufacturers and suppliers in india

Gallic acid

Properties

Melting point:: 251 °C (dec.) (lit.)

Boiling point:: 259.73°C (rough estimate)

Density: 1.694

vapor pressure: 0Pa at 25℃

refractive index: 1.5690 (estimate)

storage temp.: 2-8°C

solubility: Methanol (Slightly), Water (Slightly, Heated)

pka: 4.41(at 25℃)

form: Powder

color: Off-white

PH: 3.75(1 mM solution);3.22(10 mM solution);2.71(100 mM solution)

Water Solubility: 12 g/L cold water

Merck: 14,4345

BRN: 2050274

Stability:: Stability Stable, but may discolour upon exposure to light. Hygroscopic. Incompatible with strong oxidizing agents, strong bases, acid chlorides, acid anhydrides.

InChIKey: LNTHITQWFMADLM-UHFFFAOYSA-N

LogP: 0.7

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H315-H319-H335

Precautionary statements: P302+P352-P305+P351+P338

Hazard Codes: Xi

Risk Statements: 36/37/38

Safety Statements: 26-36-24/25-37/39

WGK Germany: 2

RTECS: LW7525000

F: 8-9-23

TSCA: Yes

HS Code: 29182900

Toxicity: LD50 in rabbits (g/kg): 5.0 orally (Dollahite)

Use

The production of gallic acid is challenging. Conventionally, it has been produced by acid hydrolysis of tannic acid. However, this process is expensive due to low yields and high impurities. To overcome this problem, microbial production of gallic acid has been suggested. For example, in a solid-state fermentation of Teri pod cover powder containing tannin using Rhizopus oryzae, a yield of 90.9 % based on the tannin content of 58 % of the substrate was observed. In a submerged culture of Aspergillus aceleatus DBF9 growing on a medium with 3 % tannin, a maximal product concentration of 6.8 g.L-1 was reported. With tannic acid, even higher product concentrations of up to 25 g.L-1, a yield of 0.83 g of gallic acid per gram of tannic acid, and a productivity of 0,56 g.L-1.h-1 were shown using Apergillus fischeri MTCC 150 in submerged cultivation. An alternative is the enzymatic hydrolysis of tannic acids using tannase produced by microorganisms (e.g. Aspergillus fischeri or R. oryzae). For example, propyl gallate could be produced using a tannase from Emericela nidulans immobilized on ionic and covalent supports.