Geldanamycin
Geldanamycin
- CAS:
- 30562-34-6
- MF:
- C29H40N2O9
- MW:
- 560.64
Suppliers by country/region
Company Type
Properties
- Melting point:
- 255 °C
- Boiling point:
- 627.87°C (rough estimate)
- Density
- 1.2443 (rough estimate)
- refractive index
- 1.5800 (estimate)
- Flash point:
- 87℃
- storage temp.
- -20°C
- solubility
- DMSO: soluble
- form
- powder
- pka
- 8.42±0.70(Predicted)
- color
- yellow to orange
- λmax
- 305nm(MeOH)(lit.)
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months
Safety Information
- Symbol(GHS)
GHS07,GHS08
- Signal word
- Warning
- Hazard statements
- H303-H227
- Precautionary statements
- P210e-P280a-P370+P378a-P403+P235-P501a
- Hazard Codes
- T,Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-27-36/37/39-24/25
- WGK Germany
- 2
- RTECS
- LX8920000
- HS Code
- 29419090
Use
Geldanamycin is benzoquinone ansamycin antibiotic isolated from Streptomyces hygroscopicus. It is a potent antitumor metabolite that acts by binding to the 90-kDa heat-shock protein (Hsp90) essential to maintain the conformation, stability, activity and cellular localisation of several key oncogenic proteins such as ERBB2, C-RAF, CDK4, AKT/PKB, steroid hormone receptors, mutant p53, HIF-1α, survivin and telomerase hTERT.
6 India supplier list of "Geldanamycin"
- Product Name:GeldanamycinReadyMadeSolution
- Products Intro:Brand:sigma aldrich | Product Number:SML1278 | Purity:1?mg/mL,fromStreptomyceshygroscopicus
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Geldanamycin 97% (HPLC), powder
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.091334
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Geldanamycin(GLD),98%
- Products Intro:Brand:trivenichemical | Product Number:23813
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Geldanamycin
- Products Intro:Brand:ajchemicals | Product Number:JDH-30608 | Purity:98+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Geldanamycin
- Products Intro:Brand:clearsynth | Product Number:CS-T-55230
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Geldanamycin
- Products Intro:Brand:pharmaffiliates | Product Number:PA0766000
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:Geldanamycin
- Products Intro:Brand:tcichemicals | Product Number:G0334
- Company Type: Reagent
- Country/Region: New Delhi,INDIA
- Product Name:Geldanamycin
- Company Type: Reagent
- Country/Region: Hyderabad,INDIA
- Product Name:Geldanamycin
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Geldanamycin
- Company Type: Reagent
- Country/Region: Haryana,INDIA