Gestrinone
Gestrinone
- CAS:
- 16320-04-0
- MF:
- C21H24O2
- MW:
- 308.41
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Properties
- Melting point:
- 150-152°C
- alpha
- D20 +84.6° (c = 0.41 in methanol)
- Boiling point:
- 388.8°C (rough estimate)
- Density
- 1.1040 (rough estimate)
- refractive index
- 1.4900 (estimate)
- storage temp.
- -20°C Freezer
- solubility
- DMF:20.0(Max Conc. mg/mL);64.85(Max Conc. mM)
DMSO:35.0(Max Conc. mg/mL);113.48(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);64.85(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:5):0.25(Max Conc. mg/mL);81.06(Max Conc. mM)
Water:1.0(Max Conc. mg/mL);3.24(Max Conc. mM)
- form
- A crystalline solid
- pka
- 12.76±0.40(Predicted)
- Merck
- 14,4415
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C21H24O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,9,11,13,18-19,23H,3,5-8,10,12H2,1H3/t18-,19+,20+,21+/m1/s1
- InChIKey
- BJJXHLWLUDYTGC-ANULTFPQSA-N
- SMILES
- C1C2C(CC[C@]3([H])C=2C=C[C@@]2(CC)[C@@]3([H])CC[C@]2(C#C)O)=CC(=O)C1
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Danger
- Hazard statements
- H360-H362
- Precautionary statements
- P201-P260-P263-P264-P270-P308+P313
- RTECS
- JF7964000
- Toxicity
- mouse,LDLo,intraperitoneal,1gm/kg (1000mg/kg),BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLDBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)GASTROINTESTINAL: OTHER CHANGES,Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 16, Pg. 701, 1988.
Use
Gestrinone is a synthetic steroid with antiprogesterone and antiestrogenic activities. It is reported to be useful in the treatment of endometriosis and uterine leiom yomas.
1 India supplier list of "Gestrinone"
- Product Name:Gestrinone
- Products Intro:Purity: >98.0% | Package: 100mg
- Company Type: Reagent
- Country/Region: New Delhi,INDIA
- Product Name:Gestrinone
- Products Intro:Brand:pharmaffiliates | Product Number:PA070760000
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:Gestrinone
- Products Intro:Purity: 0.98 | Package: 5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pimobendan,Trilostane,Fulvestrant,Fluralaner,Afoxolaner
- Product Name:Gestrinone
- Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Gestrinone
- Company Type: Service provider
- Country/Region: CHINA
- Main Products: UDDA
- Product Name:gestrinone
- Products Intro:Purity: 0.99 | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Gestrinone
- Products Intro:Purity: 98% | Package: 1KG;3.07USD
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Gestrinone
- Products Intro:Package: 1g; 5g; 25g; 1kg; 5kg; 25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: pharmaceuticals,intermediates,fine chemicals,screening compounds,building blocks
- Product Name:Gestrinone
- Products Intro:Purity: 99%|Package: 1kg;0.00;USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: SARMS,Peptides,Nootropics,Pre-workouts,Nutrition supplements
$0.00/ 1kg
- Product Name:Gestrinone
- Products Intro:Package: 1KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pregabalin,1-Phenyl-2-nitropropene,4-Chlorobenzophenone,N-(tert-Butoxycarbonyl)-4-piperidone,tert-Butyl 4-anilinopiperidine-1-carboxylate