GLIOTOXIN
GLIOTOXIN
- CAS:
- 67-99-2
- MF:
- C13H14N2O4S2
- MW:
- 326.39
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Properties
- Melting point:
- 221°C (rough estimate)
- Boiling point:
- 699.7±55.0 °C(Predicted)
- alpha
- D25 -290° (c = 0.08 in ethanol)
- Density
- 1.4069 (rough estimate)
- refractive index
- 1.6510 (estimate)
- Flash point:
- 2℃
- storage temp.
- 2-8°C
- solubility
- chloroform: 10 mg/mL, clear, colorless
- form
- White solid
- pka
- 12.90±0.40(Predicted)
- color
- Monoclinic crystals from MeOH
- Merck
- 13,4454
- BRN
- 50675
- Stability:
- Stable for 2 yeara as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H301
- Precautionary statements
- P301+P310
- Hazard Codes
- T,Xn,F
- Risk Statements
- 25-36-20/21/22-11
- Safety Statements
- 36/37/39-45-36/37-16
- RIDADR
- UN 3462 6.1/PG 3
- WGK Germany
- 3
- RTECS
- KB4725000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29419090
- Toxicity
- LD50 oral in mouse: 67mg/kg
Use
Gliotoxin is a sulfur-containing mycotoxin produced by species of fungi and pathogens of humans. Gliotoxin exhibits inhibitory activities against histone H3K9 methyltransferase, a key enzyme in the re gulation of transcriptional activity by writing epigenetic marks. Gliotoxin also exhibits immunosuppressive properties by causing apoptosis of cells of the immune system. In addition, various studies suggests Gliotoxin may also be a potential anti-inflammatory, antibiotic, antifungal and antiviral agent.
0 India supplier list of "GLIOTOXIN"
- Product Name:Gliotoxin,Gladiocladiumfimbriatum-CAS67-99-2-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:371715 | Purity:Animmunosuppressivesecondarymetaboliteproducedbyseveralpathogenicfungi.
- Company Type: Trader
- Country/Region: Bangalore,INDIA