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Indometacin

Indometacin

CAS:
53-86-1
MF:
C19H16ClNO4
MW:
357.79

Properties

Melting point:
158-162 °C
Boiling point:
499.4±45.0 °C(Predicted)
Density 
1.2135 (rough estimate)
refractive index 
1.6800 (estimate)
storage temp. 
Store at RT
solubility 
ethanol: 50 mg/mL, clear, yellow-green
pka
4.5(at 25℃)
form 
White to off-white powder
color 
White to Light yellow to Light orange
Water Solubility 
Soluble in acetone (40 mg/mL - clear, yellow solution), ethanol (20 mg/mL), ether, castor oil; Soluble in chloroform (50 mg/mL - clear, yellow, extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water.
Sensitive 
Light Sensitive
Merck 
14,4968
BRN 
497341
BCS Class
2
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
CGIGDMFJXJATDK-UHFFFAOYSA-N

Safety Information

Symbol(GHS) 

GHS06
Signal word 
Danger
Hazard statements 
H300
Precautionary statements 
P264-P301+P310
Hazard Codes 
T+,Xi,T
Risk Statements 
28-36/37/38-39/23/24/25-23/24/25
Safety Statements 
28-36/37-45-36-26
RIDADR 
UN 2811 6.1/PG 1
WGK Germany 
3
RTECS 
NL3500000
8-10
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
I
HS Code 
29339900
Toxicity
LD50 i.p. in rats: 13 mg/kg (Klaassen)

Use

Indometacin was introduced in 1963 and it is one of the first NSAIDs. Convulsions are rarely reported in relation with the use of this group of agents. Indometacin farnesil is a pro-drug of indometacin, and the occurrence of gastro-intestinal adverse effects could be expected. See also under nonsteroidal antiinflammatory agents.

55 India supplier list of "Indometacin"

  • Product Name:Indomethacin
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:Indomethacin
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Trader
  • Country/Region: Gujarat,INDIA
  • Product Name:Acemetacin EP Impurity B (Indomethacin)
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Gujarat,INDIA
  • Product Name:Indomethacin
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Gujarat,INDIA
  • Product Name:INDOMETHACIN 10% PELLETS
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Hyderabad,INDIA
  • Product Name:Indomethacin
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Mumbai,INDIA
  • Product Name:Indomethacin
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Karnataka,INDIA
  • Product Name:Indomethacin
  • Products Intro:Purity: 99% | Package: 1kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Kerela,INDIA
  • Product Name:Indomethacin-CAS53-86-1-Calbiochem
  • Products Intro:Brand:sigma aldrich | Product Number:405268 | Purity:Anon-steroidalanti-inflammatory,cellpermeable,antipyreticagent.
  • Company Type: Trader
  • Country/Region: Bangalore,INDIA
  • Product Name:Indometacin 98% (HPLC)
  • Products Intro:Brand:Glrinnovations | OriginalID:GLR19.040957
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA

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