JASPLAKINOLIDE
JASPLAKINOLIDE
- CAS:
- 102396-24-7
- MF:
- C36H45BrN4O6
- MW:
- 709.67
Suppliers by country/region
Properties
- Melting point:
- 110℃ (decomposition)
- storage temp.
- -20°C
- solubility
- DMSO: >2mg/mL
- form
- Off-white solid
- color
- off white to beige
Safety Information
- Hazard statements
- H413
- Precautionary statements
- P273-P501
- RIDADR
- 3172
- WGK Germany
- 3
- RTECS
- GX7000000
- HazardClass
- 6.1(b)
- PackingGroup
- III
Use
Jasplakinolide is a natural macrocyclic peptide first isolated from a marine sponge. It potently inhibits the proliferation of PC3 prostate carcinoma cells (IC50 = 35 nM) by binding F-actin (KD = 15 nM). This binding of jasplakinolide to actin, which is competitive with phalloidin, stabilizes actin filaments in vitro but disrupts actin filaments and induces irregular polymerization of monomeric actin in vivo. This compound is used to investigate the role of actin in diverse cellular roles, such as motility, transport, and development.
0 India supplier list of "JASPLAKINOLIDE"
- Product Name:Jasplakinolide
- Products Intro:Brand:sigma aldrich | Product Number:J4580 | Purity:≥97%(HPLC)
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Jasplakinolide
- Products Intro:Brand:clearsynth | Product Number:CS-T-56948
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Jasplakinolide
- Products Intro:Purity: 98.00% | Package: 100 mg；500 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:Jasplakinolide
- Products Intro:Purity: 95%+
- Company Type: Reagent
- Country/Region: UNITED STATES
- Product Name:Jasplakinolide
- Products Intro:Purity: >=97% (HPLC) | Package: $1038.9/100μg;Bulk package | CustNote: 97% (HPLC)
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:Jasplakinolide
- Products Intro:Purity: 99% | Package: kg
- Company Type: Trader
- Country/Region: CHINA
-
100 μg$620.00
- Product Name:Jasplakinolide
- Products Intro:Brand：Sigma-Aldrich | Product Number：J4580 | Purity：≥97%(HPLC)
- Company Type: Trader
- Country/Region: UNITED STATES
-
100 µg$281.00
- Product Name:Jasplakinolide
- Products Intro:Brand：Caymanchem | Product Number：11705 | Purity：≥98%
- Company Type: Trader
- Country/Region: UNITED STATES
-
100 ug$339.00
- Product Name:Cyclo[(3R)-3-(4-hydroxyphenyl)-β-alanyl-(2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-L-alanyl-2-bromo-N-methyl-D-tryptophyl]
- Products Intro:Brand: Tocris Bioscience | Product Number: 2792 | Purity: ≥97% (HPLC)
- Company Type: Trader
- Country/Region: UNITED KINGDOM
- Product Name:Jasplakinolide
- Products Intro:Brand：glenthamls | Product Number：GL4314
- Company Type: Trader
- Country/Region: UNITED KINGDOM