KAINIC ACID manufacturers and suppliers in india

KAINIC ACID

Properties

Melting point:: 253-254 C

alpha: D24 -14.8° (c = 1.01)

Boiling point:: 353.22°C (rough estimate)

Density: 1.2177 (rough estimate)

refractive index: 1.4368 (estimate)

storage temp.: Keep in dark place,Sealed in dry,2-8°C

solubility: H₂O: soluble

form: White to off-white solid.

pka: 2.03±0.60(Predicted)

color: White

Water Solubility: Soluble to 25 mM in water

Stability:: Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.

InChI: InChI=1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1

InChIKey: VLSMHEGGTFMBBZ-OOZYFLPDSA-N

SMILES: N1C[C@H](C(C)=C)[C@H](CC(O)=O)[C@H]1C(O)=O

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H312-H332

Precautionary statements: P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501

Hazard Codes: Xn

Risk Statements: 20/21/22

Safety Statements: 22-24/25-36

WGK Germany: 3

Use

Purify the acid by adsorbing on to a strongly acidic ion-exchange resin (Merck), elute the diacid with aqueous M NaOH, the eluate is evaporated, H2O is added, and filtered through a weakly acidic ion-exchange resin (Merck). The filtrate is then evaporated and recrystallised from EtOH. Its solubility is 0.1g in 1mL of 0.5N HCl. (±)--Kainic acid is recrystallised from H2O with m 230-260o. UV (MeOH): 219 (log 3.9); max 1HNMR (CCl4, 100MHz, Me4Si standard) : 1.64 (s 1H), 1.70 (s 3H), 3.24 (d J 7.5, 2H), 3.3-4.2 (1H), 3.70 (s 3H), 3.83 (s 3H), 4.35 (dd J 7.5, J 14.5, 1H), 5.21 (t J 7.5, 1H), 7.26 (t J 7.5, 1H). [Oppolzer & Andres Helv Chim Acta 62 2282 1979, Beilstein 22 III/IV 1523.]