Ketoconazole
Ketoconazole
- CAS:
- 65277-42-1
- MF:
- C26H28Cl2N4O4
- MW:
- 531.43
Suppliers by country/region
- India(200)
- CHINA(351)
- United States(95)
- United Kingdom(26)
- Canada(13)
- South Korea(3)
- Germany(16)
- Switzerland(4)
- Europe(2)
- Slovakia(1)
- France(5)
- Ukraine(1)
- Japan(3)
- Mexico(3)
- Philippines(1)
- Spain(9)
- Slovenia(1)
- Austria(3)
- Brazil(6)
- Belgium(6)
- Australia(1)
- Greece(1)
- Nigeria(1)
- Indonesia(1)
- The Netherlands(1)
- Poland(2)
- Italy(2)
- Argentina(1)
- Singapore(1)
- Czech Republic(1)
- Malaysia(1)
- Nepal(1)
- Egypt(1)
- Jordan(1)
- United Arab Emirates(1)
Company Type
Properties
- Melting point:
- 148-152 °C
- Boiling point:
- 753.4±60.0 °C(Predicted)
- Density
- 1.4046 (rough estimate)
- refractive index
- -10.5 ° (C=0.4, CHCl3)
- Flash point:
- 9℃
- storage temp.
- 2-8°C
- solubility
- methanol: soluble50mg/mL
- pka
- pKa 3.25/6.22(H2O,t =25,I=0.025) (Uncertain)
- form
- Off-white solid
- color
- white to light yellow
- optical activity
- [α]20/D -1 to 1°, c = 4 in methanol
- Water Solubility
- Soluble in DMSO, ethanol, chloroform, water, and methanol.
- Merck
- 14,5302
- BCS Class
- 2
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
- InChIKey
- XMAYWYJOQHXEEK-OZXSUGGESA-N
- LogP
- 4.350
Safety Information
- Symbol(GHS)
GHS06,GHS08,GHS09
- Signal word
- Danger
- Hazard statements
- H301-H360F-H373-H410
- Precautionary statements
- P201-P202-P260-P264-P273-P301+P310
- Hazard Codes
- T,N,F
- Risk Statements
- 25-36/37/38-23/24/25-50/53-48/22-60-39/23/24/25-11
- Safety Statements
- 36-45-36/37/39-26-61-60-53-36/37-16-7
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- TK7912300
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29349990
- Toxicity
- LD50 in mice, rats, guinea pigs, dogs (mg/kg): 44, 86, 28, 49 i.v.; 702, 227, 202, 780 orally (Heel)
Use
Ketoconazole is used to treat candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis. Ketoconazole is an antifungal agent. It inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor.
200 India supplier list of "Ketoconazole"
- Product Name:Ketoconazole
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:KETOCONAZOLE SODIUM
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Ketoconazole
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Uttar Pradesh,INDIA
- Product Name:Ketoconazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Tamil Nadu,INDIA
- Product Name:Ketoconazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Ketoconazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Karnataka,INDIA
- Product Name:Ketoconazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Bangalore,INDIA
- Product Name:Ketoconazole
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: NaviMumbai,INDIA
- Product Name:Ketoconazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Ketoconazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA