Lafutidine
Lafutidine
- CAS:
- 118288-08-7
- MF:
- C22H29N3O4S
- MW:
- 431.55
Suppliers by country/region
Company Type
Properties
- Melting point:
- 92.7-94.9°
- Boiling point:
- 704.2±60.0 °C(Predicted)
- Density
- 1.252±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- Water Solubility
- Insoluble in water
- solubility
- DMF:5.0(Max Conc. mg/mL);11.59(Max Conc. mM)
DMSO:48.67(Max Conc. mg/mL);112.77(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:10):0.09(Max Conc. mg/mL);0.21(Max Conc. mM)
Ethanol:9.0(Max Conc. mg/mL);20.86(Max Conc. mM)
- form
- powder to crystal
- pka
- 13.13±0.46(Predicted)
- color
- White to Orange to Green
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
- Safety Statements
- 24/25
- HS Code
- 29349990
Use
Lafutidine is a second generation of H2-receptor antagonist. H2-receptor antagonist can strongly inhibit gastric acid secretion compared with conventional drugs such as antacids. Unlike conventional H2-receptor antagonist, lafutidine inhibits gastric acid secretion during daytime as well as nighttime in clinical studies in humans. Lafutidine also has gastroprotective activity independent of its acid antisecretory efficacy, preventing noxious agent-induced gastric mucosal injury and accelerating the repair process following gastric mucosal damage. It also protects experimentally induced reflux esophagitis, indomethacin-induced intestinal, and dextran sulfate sodium-induced colonic inflammation. Lafutidine is used for gastric and duodenal ulcers. It is also confirmed that lafutidine can be used as an empiric treatment and superior efficacy for primary care practice patients with dyspepsia.
13 India supplier list of "Lafutidine"
- Product Name:Lafutidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Lafutidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Lafutidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Lafutidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Laflutidine
- Products Intro:Brand:pharmaffiliates | Product Number:PA1285000
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:Lafutidine
- Company Type: Reagent
- Country/Region: Mumbai,INDIA
- Product Name:Lafutidine
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:Lafutidine
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Lafutidine API
- Company Type: Reagent
- Country/Region: Ahmedabad,INDIA
- Product Name:Lafutidine
- Products Intro:Brand:ajchemicals | Product Number:JDH-31703 | Purity:98+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA