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Lafutidine

Lafutidine

CAS:
118288-08-7
MF:
C22H29N3O4S
MW:
431.55

Properties

Melting point:
92.7-94.9°
Boiling point:
704.2±60.0 °C(Predicted)
Density 
1.252±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
Water Solubility 
Insoluble in water
solubility 
DMF:5.0(Max Conc. mg/mL);11.59(Max Conc. mM)
DMSO:48.67(Max Conc. mg/mL);112.77(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:10):0.09(Max Conc. mg/mL);0.21(Max Conc. mM)
Ethanol:9.0(Max Conc. mg/mL);20.86(Max Conc. mM)
form 
powder to crystal
pka
13.13±0.46(Predicted)
color 
White to Orange to Green

Safety Information

Symbol(GHS) 
GHS hazard pictograms
GHS07
Signal word 
Warning
Hazard statements 
H302-H315-H319-H335
Precautionary statements 
P261-P305+P351+P338
Safety Statements 
24/25
HS Code 
29349990

Use

Lafutidine is a second generation of H2-receptor antagonist. H2-receptor antagonist can strongly inhibit gastric acid secretion compared with conventional drugs such as antacids. Unlike conventional H2-receptor antagonist, lafutidine inhibits gastric acid secretion during daytime as well as nighttime in clinical studies in humans. Lafutidine also has gastroprotective activity independent of its acid antisecretory efficacy, preventing noxious agent-induced gastric mucosal injury and accelerating the repair process following gastric mucosal damage. It also protects experimentally induced reflux esophagitis, indomethacin-induced intestinal, and dextran sulfate sodium-induced colonic inflammation. Lafutidine is used for gastric and duodenal ulcers. It is also confirmed that lafutidine can be used as an empiric treatment and superior efficacy for primary care practice patients with dyspepsia.

13 India supplier list of "Lafutidine"

Ralington Pharma
  • Product Name:Lafutidine
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
Bajaj Healthcare Ltd
  • Product Name:Lafutidine
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
Afton Pharma
  • Product Name:Lafutidine
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
Hetero Drugs Limited
  • Product Name:Lafutidine
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
  • Company Type: Manufacturer
  • Country/Region: Telangana,INDIA
Pharmaffiliates Analytics and Synthetics P. Ltd
  • Product Name:Laflutidine
  • Products Intro:Brand:pharmaffiliates | Product Number:PA1285000
  • Company Type: Trader
  • Country/Region: Haryana,INDIA
Aquatic Remedies Private Limited
  • Product Name:Lafutidine
  • Company Type: Reagent
  • Country/Region: Mumbai,INDIA
Pharma Affiliates
  • Product Name:Lafutidine
  • Company Type: Reagent
  • Country/Region: Haryana,INDIA
  • Product Name:Lafutidine
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
Angle Biopharma
  • Product Name:Lafutidine API
  • Company Type: Reagent
  • Country/Region: Ahmedabad,INDIA
  • Product Name:Lafutidine
  • Products Intro:Brand:ajchemicals | Product Number:JDH-31703 | Purity:98+%
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA

Lafutidine Related Search:

RanitidineFamotidineOmeprazoleAcetamideFuranLomerizinep-Nitrophenyl 2-(Furfurylsulfinyl)acetate LACTITOLLafutidine
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