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Lafutidine

CAS No.: 118288-08-7

Chemical Name:: Lafutidine

Synonyms: Stogar;LACTITOL;frg-8813;Protecadin;LAFUTIDINE;Laflutidine;118288-08-07;enyl)acetamide;Lafutidine API;Lafutidine Tablets

CBNumber:: CB4297653

Molecular Formula:: C22H29N3O4S

Molecular Weight:: 431.55

MOL File:: 118288-08-7.mol

MSDS File:: SDS

Modify Date:: 2023/6/8 9:03:01

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Lafutidine Properties

Melting point	92.7-94.9°
Boiling point	704.2±60.0 °C(Predicted)
Density	1.252±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Store in freezer, under -20°C
Water Solubility	Insoluble in water
solubility	DMF:5.0(Max Conc. mg/mL);11.59(Max Conc. mM) DMSO:48.67(Max Conc. mg/mL);112.77(Max Conc. mM) DMSO:PBS (pH 7.2) (1:10):0.09(Max Conc. mg/mL);0.21(Max Conc. mM) Ethanol:9.0(Max Conc. mg/mL);20.86(Max Conc. mM)
form	powder to crystal
pka	13.13±0.46(Predicted)
color	White to Orange to Green
CAS DataBase Reference	118288-08-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P305+P351+P338

Safety Statements

24/25

HS Code

29349990

NFPA 704

	0
1		0

Lafutidine price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemicals (India)	L0341	Lafutidine	118288-08-7	25MG	₹2200	2022-05-26	Buy
TCI Chemicals (India)	L0341	Lafutidine	118288-08-7	250MG	₹6600	2022-05-26	Buy
TCI Chemicals (India)	L0341	Lafutidine	118288-08-7	1G	₹14200	2022-05-26	Buy

Product number	Packaging	Price	Buy
L0341	25MG	₹2200	Buy
L0341	250MG	₹6600	Buy
L0341	1G	₹14200	Buy

Lafutidine Chemical Properties,Uses,Production

Description

Lafutidine was launched in Japan for the treatment of gastritis, reflux oesophagitis and peptic ulcers. It can be prepared in eight steps from 4-(2-tetrahydropyranyloxy)-2(Z)-butenl- ol. Lafutidine is a potent and longer-acting H₂ antagonist compared to other marketed compounds of its class such as cimetidine and famotidine. In contrast to other commercially available H₂ antagonists, lafutidine also exerts a gastroprotective action probably via capsaicin-sensitive afferent nerves. It was clinically effective in the treatment of nonsteroidal antiinflammatory drug-induced ulcer in patients refractory to existing antiulcer agents.

Uses

Lafutidine, a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion

Lafutidine Preparation Products And Raw materials

Raw materials

Pyridine, 4-(1-piperidinylmethyl)-2-[[(2Z)-4-[(tetrahydro-2H-pyran-2-yl)oxy]-2-buten-1-yl]oxy]- 118289-23-9 2-(4-((4-(1,3-dioxolan-2-yl)pyridin-2-yl)oxy)but-2-en-1-yl)isoindoline-1,3-dione 118287-95-9 118289-22-8

4-((4-(1,3-dioxolan-2-yl)pyridin-2-yl)oxy)but-2-en-1-ol 4-(1,3-dioxolan-2-yl)-2-((4-((tetrahydro-2H-pyran-2-yl)oxy)but-2-en-1-yl)oxy)pyridine Piperidine

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Preparation Products

Lafutidine Suppliers

Global( 305)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Hetero Drugs Limited	+91-4023704923 +91-4023704923	Telangana, India	296	58	Inquiry
Bajaj Healthcare Ltd	+91-2266177400 +91-2266177400	Maharashtra, India	86	58	Inquiry
Afton Pharma	+91-9712000202 +91-9712000202	Gujarat, India	63	58	Inquiry
Ralington Pharma	+91-7948911722 +91-9687771722	Gujarat, India	1350	58	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6778	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6522	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6761	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6707	30	Inquiry

Supplier	Advantage
Hetero Drugs Limited	58
Bajaj Healthcare Ltd	58
Afton Pharma	58
Ralington Pharma	58
TCI Chemicals (India) Pvt. Ltd.	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
SynZeal Research Pvt Ltd	58
Pharma Affiliates	58
CLEARSYNTH LABS LTD.	58
CHEMSWORTH	30

Lafutidine Spectrum

Lafutidine(118288-08-7)¹HNMR

118288-08-7(Lafutidine)Related Search:

Omeprazole Famotidine Ranitidine Lafutidine N-{4-[4-(PIPERIDINOMETHYL)PYRIDYL-2-OXY]-CIS-2-BUTENE}PHTHALIMIDE MALEIC ACID(INTERMEDIATE FOR LAFUTIDINE)

LACTITOL MONOHYDRATE,LACTITOL H2O,D-LACTITOL MONOHYDRATE,LACTITOL MONOHYDRATE 99% p-Nitrophenyl 2-(Furfurylsulfinyl)acetate 4-[4-(Piperidinomethyl)pyridyl-2-oxy]-cis-2-butenamine 2-ALLYLOXYPYRIDINE LACTITOL

(Z)-4-[(TETRAHYDRO-2H-PYRAN-2-YL)OXY]-2-BUTEN-1-OL (PREPARATION FOR LAFUTIDINE) Lomerizine Furan Acetamide 2-Butene

2(1H)-Pyridinone,4-(aminomethyl)-(9CI) 2-((FURAN-2-YL)METHYLSULFINYL)-N-((Z)-4-HYDROXYBUT-2-ENYL)ACETAMIDE N-(PYRIDIN-4-YLMETHYL)BUTAN-1-AMINE

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n-(4-(4-piperidinylmethyl)pyridyl-2-oxy)butenyl-2-(furfurylsulfinyl)acetamide 2-((Furan-2-ylMethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylMethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetaMide (Z)-2-((Furan-2-ylMethyl)sulfinyl)-N-(4-((3-(piperidin-1-ylMethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetaMide Adefovir Dipivioxil (Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((3-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl) (Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((3-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1- LAFUTIDINE(SUBJECTTOPATENTFREE) 118288-08-07 LACTITOL 2-[(2-Furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-buten-1-yl]acetamide Laflutidine Protecadin Stogar LAFUTIDINE (+-)-2-(furfurylsulfinyl)-n-(4-(4-(piperidinomethyl)-2-pyridyl)oxy-(z)-2-but (z)-inyl)oxy)-2-butenyl) acetamide,2-((2-furanylmethyl)sulfinyl)-n-(4-((4-(1-piperidinylmethyl)-2-pyrid enyl)acetamide frg-8813 2-[(2-Furanylmethyl)sulfinyl]-N-[(2Z)4-[[4-(1-piperidinylmethyl)-2-pyridinyl] oxy]-2-butenyl]-acetamide 2-(2-furanylmethylsulfinyl)-N-[2-hydroxy-4-[4-(4-piperidinylmethyl)-2-pyridinyl]but-1-enyl]acetamide Lafutidine Lafutidine (Z)-2-[(Furan-2-ylmethyl)sulfinyl]-N-[4-[[4-(piperidin-1-ylmethyl)pyridin-2-yl]oxy]but-2-en-1-yl]acetamide Lafutidine USP/EP/BP 2-(furan-2-ylmethylsulfinyl)-N-[(Z)-4-[4-(piperidin-1-ylmethyl)pyridin-2-yl]oxybut-2-enyl]acetamide (+)-(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide Lafutidine (FRG-8813) LafutidineQ: What is Lafutidine Q: What is the CAS Number of Lafutidine Q: What is the storage condition of Lafutidine Q: What are the applications of Lafutidine Lafutidine API R)-Palonosetron Hydrochloride Lafutidine Tablets 118288-08-7 118288-89-7 118288-08-07 118288-08-1 18288-08-7 C22H29N3O4S Other APIs Active Pharmaceutical Ingredients Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds