lenvatinib Mesylate
Lenvatinib Mesylate
- CAS:
- 857890-39-2
- MF:
- C22H23ClN4O7S
- MW:
- 522.95862
Suppliers by country/region
Company Type
Properties
- Melting point:
- >220°C (dec.)
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- InChIKey
- HWLFIUUAYLEFCT-UHFFFAOYSA-N
- SMILES
- O=C(N)C1C=C2C(N=CC=C2OC2C=C(Cl)C(NC(=O)NC3CC3)=CC=2)=CC=1OC.CS(=O)(O)=O
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Use
Lenvatinib mesylate (lenvatinib) is an orally available, receptor‐type tyrosine kinase inhibitor, which was developed at Eisai in 2015. It was approved by the FDA in 2015 for the treatment of differentiated thyroid cancer that is either locally recurrent, metastatic, or progressive and did not respond to radioactive iodine treatment. In May 2016, the FDA approved the drug as a combination therapy with everolimus for the treatment of advanced renal cell carcinoma. Because VEGF (and fibroblast growth factor receptors, known as FGFRs) are thought to play a role in cardiovascular signaling pathways, VEGF2R and FGFR inhibition are thought to be the mechanisms behind the primary side effect of lenvatinib mesylate, which is hypertension.
9 India supplier list of "Lenvatinib Mesylate"
- Product Name:Lenvatinib Mesylate (Form C and MIBK Solvate)
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:Lenvatinib mesylate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Haryana,INDIA
- Product Name:Lenvatinib mesylate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Lenvatinibmesylate
- Products Intro:Brand:sigma aldrich | Product Number:SML3017 | Purity:≥98%(HPLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Lenvatinib mesylate 95%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.193349
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:LenvatinibMesylate
- Products Intro:Brand:synzeal | Product Number:122704805
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Lenvatinibmesylate
- Products Intro:Brand:clearsynth | Product Number:CS-ED-01320
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:LENVATINIB MESYLATE
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:lenvatinib Mesylate
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:LENVATINIB MESYLATE
- Company Type: Manufacturer
- Country/Region: New Delhi,INDIA