LY2940680
LY2940680
- CAS:
- 1258861-20-9
- MF:
- C26H24F4N6O
- MW:
- 512.5
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Properties
- Boiling point:
- 703.5±60.0 °C(Predicted)
- Density
- 1.39
- storage temp.
- Store at -20°C
- solubility
- insoluble in H2O; ≥5.2 mg/mL in EtOH with ultrasonic; ≥51.3 mg/mL in DMSO with gentle warming and ultrasonic
- form
- crystalline solid
- pka
- 7.94±0.30(Predicted)
- color
- White to off-white
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Danger
- Hazard statements
- H360-H373
- Precautionary statements
- P260-P314-P501
Use
Smoothened (Smo) is a GPCR-like receptor that, with Patched, mediates hedgehog (Hh) signaling to regulate gene expression through the Gli transcription factors. LY2940680 is an antitumor agent that binds to the human Smo receptor and inhibits Sonic Hh-induced Gli1 expression (IC50 = ~2.4 nM in vitro). The potential anticancer activity of LY2940680 is currently under clinical investigation.[Cayman Chemical]
0 India supplier list of "LY2940680"
$1.00/ 1KG
- Product Name:LY2940680
- Products Intro:Purity: 99% | Package: 1KG;1USD
- Company Type: Trader
- Country/Region: CHINA