methicillin
methicillin
- CAS:
- 61-32-5
- MF:
- C17H20N2O6S
- MW:
- 380.42
Suppliers by country/region
Company Type
Properties
- Boiling point:
- 640.0±55.0 °C(Predicted)
- Density
- 1.44±0.1 g/cm3(Predicted)
- pka
- pKa 2.77± 0.04(H2O,t = 25,c=0.0097) (Uncertain)
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P330-P501
- Hazard Codes
- Xn
- Risk Statements
- 22
- WGK Germany
- 3
- RTECS
- XH2379000
Use
2,6-Dimethoxyphenylpenicillin; methicillin (international non-proprietary name). The first β-lactamase-resistant semisynthetic penicillin. It was initially used widely but has been superseded by other group 3 members and is no longer commercially available. It is less active than benzylpenicillin or other group 3 penicillins. It is very stable to staphylococcal β-lactamase and is active against β-lactamaseproducing strains of Staph. aureus that do not produce a functional PBP 2a. Resistance is common among staphylococci, with the incidence geographically diverse. Most methicillin-resistant staphylococcal isolates display multiresistance. It is not acid resistant, and must therefore be administered parenterally. About 10% is metabolized, with 60–80% of the dose excreted in the urine. Toxicity is similar to that of other group 3 penicillins. Nephritis appears to be more common than with other penicillins.
0 India supplier list of "methicillin "
- Product Name:Meticillin;Staphcillin;Dimethoxyphenyl Penicillin;Methicillin;Metin
- Products Intro:Package: 100 mg;500 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Reagent
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
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- Product Name:methicillin
- Company Type: Trader
- Country/Region: UNITED STATES
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- Product Name:methicillin
- Company Type: Trader
- Country/Region: SWITZERLAND