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methicillin

methicillin

CAS:
61-32-5
MF:
C17H20N2O6S
MW:
380.42

Suppliers by country/region

Properties

Boiling point:
640.0±55.0 °C(Predicted)
Density 
1.44±0.1 g/cm3(Predicted)
pka
pKa 2.77± 0.04(H2O,t = 25,c=0.0097) (Uncertain)

Safety Information

Symbol(GHS) 

GHS07
Signal word 
Warning
Hazard statements 
H302
Precautionary statements 
P264-P270-P301+P312-P330-P501
Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
RTECS 
XH2379000

Use

2,6-Dimethoxyphenylpenicillin; methicillin (international non-proprietary name). The first β-lactamase-resistant semisynthetic penicillin. It was initially used widely but has been superseded by other group 3 members and is no longer commercially available. It is less active than benzylpenicillin or other group 3 penicillins. It is very stable to staphylococcal β-lactamase and is active against β-lactamaseproducing strains of Staph. aureus that do not produce a functional PBP 2a. Resistance is common among staphylococci, with the incidence geographically diverse. Most methicillin-resistant staphylococcal isolates display multiresistance. It is not acid resistant, and must therefore be administered parenterally. About 10% is metabolized, with 60–80% of the dose excreted in the urine. Toxicity is similar to that of other group 3 penicillins. Nephritis appears to be more common than with other penicillins.

0 India supplier list of "methicillin "

  • Product Name:Meticillin;Staphcillin;Dimethoxyphenyl Penicillin;Methicillin;Metin
  • Products Intro:Package: 100 mg;500 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
  • Company Type: Reagent
  • Country/Region: UNITED STATES
  • Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
  • 5vl$122.00
  • Product Name:MRSA Selective Supplement
  • Products Intro:Brand: Sigma-Aldrich | Product Number: 51387 | Purity: for microbiology
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Main Products: cof,mof
  • Product Name:Meticillin
  • Products Intro:Brand:dcchemicals | Product Number:DC31756
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Product Name:methicillin
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:methicillin
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Product Name:methicillin
  • Company Type: Service provider
  • Country/Region: CHINA
  • Product Name:methicillin
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:methicillin
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Product Name:MRSA Selective SuppleMent
  • Products Intro:Package: 5Mg;25Mg;100Mg;1g;5g;10g
  • Company Type: Reagent
  • Country/Region: CHINA
  • Product Name:methicillin
  • Company Type: Trader
  • Country/Region: SWITZERLAND
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