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Methyl cyanoacetate

Methyl cyanoacetate

CAS:
105-34-0
MF:
C4H5NO2
MW:
99.09

Properties

Melting point:
-13 °C
Boiling point:
204-207 °C(lit.)
Density 
1.123 g/mL at 25 °C(lit.)
vapor density 
3.41 (vs air)
vapor pressure 
0.2 mm Hg ( 20 °C)
refractive index 
n20/D 1.417(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
54g/l
form 
Liquid
pka
2.75±0.10(Predicted)
color 
Clear colorless to very slightly yellow
Water Solubility 
54 g/L (20 ºC)
Sensitive 
Light Sensitive
BRN 
773945
Dielectric constant
29.4(21℃)
LogP
-0.47 at 25℃

Safety Information

Symbol(GHS) 

GHS07
Signal word 
Warning
Hazard statements 
H319
Precautionary statements 
P264-P280-P305+P351+P338-P337+P313
Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
1
RTECS 
AG4375000
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29269095
Toxicity
guinea pig,LDLo,skin,400mg/kg (400mg/kg),"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 920, 1986.

Use

Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It may be used in the synthesis of various 1,2,5-tricarbonyl compounds. It is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate; a compound used in the synthesis of DPP-IV inhibitors for treating type-2 diabetes. In addition, it is an intermediate in the preparation of -cyanoacrylate, malononitrile, and 1,1-cyclohexanediacetic acid dyes. It is used as UV absorber or stabilizer, intermediate for pharmaceuticals. It may be used in the synthesis of various 1,2,5-tricarbonyl compounds.

45 India supplier list of "Methyl cyanoacetate"

  • Product Name:Methyl cyanoacetate, 98%
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Trader
  • Country/Region: Gujarat,INDIA
  • Product Name:Methyl cyanoacetate
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA
  • Product Name:Methyl Cyanoacetate
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:Methyl cyanoacetate
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Methyl cyanoacetate
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Hyderabad,INDIA
  • Product Name:Methylcyanoacetate
  • Products Intro:Brand:sigma aldrich | Product Number:108421 | Purity:99%
  • Company Type: Trader
  • Country/Region: Bangalore,INDIA
  • Product Name:Methyl cyanoacetate >99% (GC)
  • Products Intro:Brand:Glrinnovations | OriginalID:GLR19.070617
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:Methyl cyanoacetate
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:Methyl cyanoacetate
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:Methyl cyanoacetate
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA

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